臓器移植における再生医療の応用 Regenerative Medicine Applications in Organ Transplantation

著者名：Orlando, Giuseppe (EDT)

Academic Press（2013/10/11発売）

• 言語：ENG
• ISBN：9780123985231
• eISBN：9780123985200

Description

Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine.Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results.- Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration- Explains the importance and future potential of regenerative medicine to the transplant community- Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions

Table of Contents

Meet the EditorsPreface1. Introduction: Regenerative medicine and solid organ transplantation from a historical perspective2. Solid organ transplantation: has the promise been kept and the needs met?Principles of Regenerative Medicine and Cell, Tissue, and Organ Bioengineering3. Strategies for the specification of tissue engineering biomaterials4. Principles of Stem Cell Biology5. Principles of cell sheet technology6. Principles of bioprinting technology7. Synthetic biomaterial for regenerative medicine applications 8. Natural biomaterials for regenerative medicine applications9. Bioartificial biomaterials for regenerative medicine applications10. Bioactivated materials for cell and tissue guidance11. Biocompatibility and immune response to biomaterials12. Harnessing regenerative and immunomodulatory properties of stem cells13. Bioreactors for tissue engineering purposesKidney14. Current status of renal transplantation15. Living related renal transplantation: progress, pitfalls and promise16. Machine perfusion of kidneys donated after cardiac death: the Carrel and Lindbergh legacy17. Renal regeneration: the bioengineering approach18. Renal regeneration: the stem cell biology approach19. Renal regeneration: the developmental approachLiver20. Current status of liver transplantation21. Living related liver transplantation: progress, pitfalls and promise22. Donation after cardiac death liver transplantation23. Artificial liver support24. Liver regeneration: the bioengineering approach25. Liver regeneration: the developmental biology approach26. Liver regeneration: the stem cell approach27. Liver bioengineering using human cellsHeart28. Current status of heart transplantation29. Artificial heart support30. Heart regeneration: the bioengineering approach31. Heart regeneration: the developmental and stem cell biology approachSmall Bowel32. Current status of intestinal transplantation33. Living related small bowel transplantation: progress, pitfalls and promise34. Intestinal regeneration: the bioengineering approach35. Intestinal regeneration: the developmental biology approach36. Intestinal regeneration: stem cell approach37. Building blocks for engineering the small intestineEndocrine pancreas and islets of Langerhans38. Current status of pancreas transplantation39. Living related pancreas transplantation: progress, pitfalls and promise40. Current status of islet transplantation41. Pancreatic islets regeneration: the bioengineering approach42. Pancreatic islet regeneration: the developmental and stem cell biology approach43. Microencapsulation technology44. Autologous islets transplantationLung45. Current status of lung transplantation46. Living related lung transplantation: progress, pitfalls and promise47. Artificial Lung Support48. Lung regeneration: the bioengineering approach49. Lung regeneration: the developmental biology approach50. Lung regeneration: stem cell approachComposite tissues allotransplantationImmunosuppression-free transplantation in the regenerative medicine eraEpilogue: Organ Bioengineering and Regeneration as the new Holy Grail of Organ Transplantation