Description
Nutritional oncology is an increasingly active interdisciplinary field where cancer is investigated as both a systemic and local disease originating with the changes in the genome and progressing through a multi-step process which may be influenced at many points in its natural history by nutritional factors that could impact the prevention of cancer, the quality of life of cancer patients, and the risk of cancer recurrence in the rapidly increasing population of cancer survivors.Since the first edition of this book was published in 1999, the idea that there is a single gene pathway or single drug will provide a cure for cancer has given way to the general view that dietary/environmental factors impact the progression of genetic and cellular changes in common forms of cancer. This broad concept can now be investigated within a basic and clinical research context for specific types of cancer. This book attempts to cover the current available knowledge in this new field of nutritional oncology written by invited experts. This book attempts to provide not only the theoretical and research basis for nutritional oncology, but will offer the medical oncologist and other members of multidisciplinary groups treating cancer patients practical information on nutrition assessment and nutritional regimens, including micronutrient and phytochemical supplementation. The editors hope that this volume will stimulate increased research, education and patient application of the principles of nutritional oncology.NEW TO THIS EDITION:* Covers hot new topics of nutrigenomics and nutrigenetics in cancer cell growth * Includes new chapters on metabolic networks in cancer cell growth, nutrigenetics and nutrigenomics* Presents substantially revised chapters on breast cancer and nutrition, prostate cancer and nutrition, and colon cancer and nutrition* Includes new illustrations throughout the text, especially in the breast cancer chapter* Includes integrated insights into the unanswered questions and clearly defined objectives of research in nutritional oncology * Offers practical guidelines for clinicians advising malnourished cancer patients and cancer survivors on diet, nutrition, and lifestyle * Provides information on the role of bioactive substances, dietary supplements, phytochemicals and botanicals in cancer prevention and treatment
Table of Contents
EDITOR-IN-CHIEFContributing AuthorsPrefaceIntroduction: The Principles of Nutritional OncologyI: Biology of Nutrition and CancerChapter 1: Fundamentals of Human NutritionChapter 2: Nutrigenomics and NutrigeneticsChapter 3: Genetics and Epigenetics in Cancer BiologyChapter 4: Metabolic Networks in Cancer CellsChapter 5: Energy Balance and CancerII: Epidemiology of Nutrition and CancerChapter 6: Nutritional EpidemiologyChapter 7: Fruit and Vegetable Consumption and CancerChapter 8: Are Whole Grains Protective Against a Variety of Cancers?Chapter 9: Obesity and Cancer RiskChapter 10: Nutrition and Tobacco-Related CancersChapter 11: Alcohol and CancerChapter 12: Environmental Toxins, Nutrition, and CancerIII: Biological Approaches to Investigating Nutrition and CancerChapter 13: Endocrine and Paracrine Factors in CarcinogenesisChapter 14: Oxidation and Antioxidation in CancerChapter 15: Thiols in CancerChapter 16: Principles of Tumor ImmunologyChapter 17: Animal Models in Nutritional Oncology ResearchIV: Gene-Nutrient Interaction and Cancer PreventionChapter 18: The Challenge of Nutrition in Cancer PreventionChapter 19: Dietary AssessmentChapter 20: Prostate CancerChapter 21: Breast CancerChapter 22: Skin CancerChapter 23: Colon CancerChapter 24: Gastric CancerChapter 25: Pancreatic CancerChapter 26: Bladder CancerChapter 27: Differentiation Induction in Leukemia and LymphomaV: Bioactive Food Components and Botanical Approaches to CancerChapter 28: Dietary Supplements in Cancer Prevention and TherapyChapter 29: Dietary Fiber and CarbohydratesChapter 30: Dietary LipidsChapter 31: Calcium and Vitamin DChapter 32: Soy IsoflavonesChapter 33: Selenium and Cancer PreventionChapter 34: GlucosinolatesChapter 35: Green TeaChapter 36: GarlicChapter 37: BerriesChapter 38: Isoprenoids and Novel Inhibitors of Mevalonate Pathway ActivitiesVI: Nutritional Assessment and Support of the Cancer PatientChapter 39: Cancer Anorexia and CachexiaChapter 40: Weight Management in the Breast Cancer SurvivorChapter 41: Nutrition Support of the Adult Cancer PatientChapter 42: Assessing Endocrine Effects of Cancer and Ectopic Hormone SyndromesChapter 43: Counseling the Cancer SurvivorChapter 44: Nutritional Support and Quality of LifeVII: Nutritional Implementation Guidelines and PracticeChapter 45: Modern Statistical Methods in Clinical NutritionChapter 46: Evidence-based Practice Management in Cancer Prevention and TreatmentChapter 47: Dietary Guidelines in Cancer PreventionChapter 48: Dietary InterventionsChapter 49: Future Directions in Cancer and Nutrition Research: Gene–Nutrient Interactions, Networks, and the Xenobiotic HypothesisIndex
