分子栄養学と糖尿病 Molecular Nutrition and Diabetes : A Volume in the Molecular Nutrition Series

著者名：Mauricio, Didac (EDT)

Academic Press（2015/12/08発売）

• 言語：ENG
• ISBN：9780128015858
• eISBN：9780128017616

Description

Molecular Nutrition and Diabetes: A Volume in the Molecular Nutrition Series focuses on diabetes as a nutritional problem and its important metabolic consequences. Fuel metabolism and dietary supply all influence the outcome of diabetes, but understanding the pathogenesis of the diabetic process is a prelude to better nutritional control.Part One of the book provides general coverage of nutrition and diabetes in terms of dietary patterns, insulin resistance, and the glucose-insulin axis, while Part Two presents the molecular biology of diabetes and focuses on areas such as oxidative stress, mitochondrial function, insulin resistance, high-fat diets, nutriceuticals, and lipid accumulation. Final sections explore the genetic machinery behind diabetes and diabetic metabolism, including signaling pathways, gene expression, genome-wide association studies, and specific gene expression. While the main focus of each chapter is the basic and clinical research on diabetes as a nutritional problem, all chapters also end with a translational section on the implications for the nutritional control of diabetes.- Offers updated information and a perspective on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of diabetes mellitus- Explores how nutritional factors are involved in the pathogenesis of both type1 and type2 diabetes and their complications- Investigates the molecular and genetic bases of diabetes and diabetic metabolism through the lens of a rapidly evolving field of molecular nutrition

Table of Contents

Section 1: General and Introductory Aspects1. Nutrition and diabetes: general aspects  Ana M. Wägner, Julia Charlotte Wiebe, Rosa M. Sánchez-Hernández and Lidia García-Pérez2. Dietary patterns and insulin resistance  Marcio A. Torsoni, Adriana Souza Torsoni and Marciane Milanski3. Beta cell metabolism, insulin production and secretion; metabolic failure resulting in diabetes  Younan Chen, Vinicius Fernandes Cruzat and Philip Newsholme4. Diet-gene interactions in the development of diabetes  Jose M. Ordovas5. Pathogenesis of type 1 diabetes: role of dietary factors  Julie Christine Antvorskov, Karsten Buschard and Knud JosefsenSection 2: Molecular biology of the cell6. Oxidative stress in diabetes mellitus: molecular aspects: implications for the diet  Lu Cai7. Muscle protein in type 2 diabetes: Molecular aspects  Antonio Zorzano8. Mechanisms whereby wholegrain cereals modulate the prevention of type-2 diabetes  Knud Erik Bach Knudsen, Kjeld Hermansen, Mette Skou Hedemann and Merete Lindberg Hartvigsen9. Peroxisome proliferator activated receptors -PPARs - in glucose control  Massimo Collino and Fausto Chiazza10. High-fat diets and beta-cell dysfunction: molecular aspects  Carla B. Collares-Buzato11. Native fruits, anthocyanins in nutraceuticals and the insulin receptor/insulin receptor substrate-1/Akt/ forkhead box protein pathway  N.R.V. Dragano and Anne y Castro Marques12. Influence of dietary factors on gut microbiota: role on insulin resistance and diabetes mellitus  Gemma Xifra Villarroya, Eduardo Esteve and J.M Fernandez-Real13. Molecular aspects of Glucose regulation of pancreatic beta-cells  Rosa Gasa, Ramon Gomis, Anna Novials and Joan-Marc Servitja14. Metals and signalling in diabetes  Lu Cai15. Cocoa flavonoids and insulin signalling  Sonia Ramos, M.A. Martin and Luis Goya16. Dietary proanthocyanidin modulation of pancreatic beta-cells: molecular aspects  Montserrat Pinent, Mayte Blay, Anna Ardevol and Noemi Gonzalez-Abuin17. Dietary whey protein and Type 2 diabetes: molecular aspects  Jaime Amaya-Farfan, Priscila Neder Morato, Carolina Soares Moura and Pablo Lollo18. Dietary fatty acids and C-reactive proteins in diabetes  Giovanni Annuzzi, Ettore Griffo, Giuseppina Costabile and Lutgarda Bozzetto19. Alcoholic beverage and diabetes: cellular and molecular effects  Suzanne de la MonteSection 3: Genetic machinery and its function20. Alleles and risk of diabetes  Valeriya Lyssenko21. Micro RNAs in diabetes  Louise Torp Dalgaard, Sofia Anna Salö, Anja Elaine Sørensen and Julian Geiger22. Diabetes mellitus and intestinal Niemann-Pick C1-Like1 gene expression  W. A. Alrefai, Pooja Malhotra, Ravinder K. Gill and Pradeep K. Dudeja23. Dietary long-chain omega-3 polyunsaturated fatty acids and inflammatory gene expression in type 2 diabetes  Manohar Lal Garg24. Polymorphisms, carbohydrates, fat and type 2 diabetes: the example of insulin receptor substrate 1 (IRS1)  Jose Lopez-Miranda25. Genetic basis linking variants for diabetes and obesity with breast cancer  Vijay Kumar Kutala26. Genetic determinants of pathways underlying 25(OH) vitamin D deficiency predisposing to type 1 and type 2 diabetes mellitus  Dharambir K. Sanghera and Piers R. Blackett27. NRF2-mediated gene regulation and glucose homeostasis  Masayuki Yamamoto and Akira Uruno28. Hepatic mitochondrial fatty acid oxidation and type 2 diabetes  Abdelhak Mansouri, Wolfgang Langhans, Jean Girard and Carina Prip-Buus29. The wnt signaling pathway and glucose homeostasis  T. Jin