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Full Description
This book examines the development and applications of system biology approaches for the prevention, diagnosis, and understanding of disease mechanisms. It explores the applications of system biology in infectious diseases, including host-pathogen interaction, and the identification of targets for new therapeutics and intervention strategies. It covers the use of system biology for understanding and treating metabolic disorders towards personalized and precision medicine. The book further discusses the systems biology approaches for understanding the mechanisms of tumor progression and designing more effective cancer therapies. The chapter also reviews the current strategies in autoimmune disease treatment and highlights the opportunity that systems biology represents for the development of better and safer treatments. Importantly, the book discusses the current state of the systems-level understanding of diseases and both the therapeutic and adverse mechanisms of drug actions usingsystem biology approaches. Cutting across the disciplines, this book is a valuable source for researchers in genetics, molecular biology, cell biology, microbiology, and biomedical sciences.
Contents
Chapter 1. Introduction to Systems Biology.- Chapter 2. Systems Biology and Human Diseases.- Chapter 3. Medical applications of Systems Biology.- Chapter 4. Systems Biology for Metabolic Disorder and Diseases.- Chapter 5. Systems Biology Consortium for Infectious Diseases.- Chapter 6. Case Study Based Approaches of Systems Biology in Addressing Infectious Diseases.- Chapter 7. Systems Biology and Hospital-Associated Infections.- Chapter 8. Systems Biology Approach in Understanding Mitochondrial Disease.- Chapter 9. Systems Approaches in Identifying Disease Related Genes and Drug Targets.- Chapter 10. Systems Approach for Identifying Drug Targets by Computational Approaches.- Chapter 11. Systems Biology Approaches for Precision Medicine.- Chapter 12. Systems Biology Approaches for Autoimmune Diseases.- Chapter 13. Systems Biology - A New Era for Vaccine Development; From Deductive Towards Inductive.- Chapter 14. The Important Role of Systems biology in Neuroscience and Neurology and ItsAssociated Diseases.- Chapter 15. Computational and Experimental Approaches to Decipher the Complexity of Diseases.- Chapter 16. Complex Disease Prediction using Systems Biology Approach.- Chapter 17. Systems Biology in Understanding Human Gut Microbiome and Related Diseases Highlighting Metabolic Modeling and Analysis.- Chapter 18. Understanding Colon Cancer: Causes, Prevention, and Complementary Therapies Including Therapeutic Foods, Beverages, and Meditation.- Chapter 19. The Potential of Systems Biology to Understand the Tenets of Host-Pathogen Interaction, Toxicology and Aging.- Chapter 20. Systems Biology Approaches as a Tool in Understanding Neurodevelopmental Disorders: Some Case Studies.- Chapter 21. Systems biology Approaches for Cancer Biology.- Chapter 22. Prevention, Diagnosis, and Understanding Mechanisms of Metabolic Diseases Using Systems Biology.
