Full Description
This book shelters the central principles, cutting-edge methodologies, and incipient thought processes applied to PEGylation research. The content also expounds on the critical properties of PEG and other polymers that can be applied to formulate a prolonged-circulating nanocarrier system for the delivery of gene, nucleic acid, drugs, protein, and peptide and diagnostic agents. The book summarizes the methodologies and effects of PEGylation on drug delivery and highlights recent developments in PEGylated drugs. It also aims to present vital biopharmaceutical fates of PEGylated therapeutics and examines the approaches involved in the preparation, physicochemical properties, and biological applications of long-circulating PEGylated pharmaceutical nanocarriers. This book also cross-talks and offers expert viewpoints on mucus-penetrating PEGylated nanocarrier, reversible PEGylation of nanocarriers, and Bio-PEGylation as well as PEGylation and its alternatives. The book also deals with hottopics including the current status and regulatory aspects of PEGylated Nanoproducts, and medicinal and pharmaceutical applications of PEGylated Nanocarriers. The book provides a comprehensive literature resource for the students, biologists, chemists, toxicologists, medical researchers, scientists in industries, research institutes, universities, and consultants involved in the development and testing of new advanced medicines
Contents
Chapter 1. PEGylated Pharmaceutical Nanocarriers.- Chapter 2. Methods and Protocols for the synthesis of PEGylated Pharmaceutical Nanocarriers.- Chapter 3. Topology and internal structure of PEGylated nanocarriers.- Chapter 4. PEGylated Nanocarriers for Drug delivery applications.- Chapter 5. PEGylated Nanocarriers for Solubilization.- Chapter 6. PEGylation as a tool to alter immunological properties of Nanocarriers.- Chapter 7. PEGylated nanocarrier as a promising tool for site-specific delivery of therapeutics.- Chapter 8. PEGylated Nanocarriers for Gene delivery.- Chapter 9. PEGylated Nanocarrier system for nucleic acid delivery.- Chapter 10. PEGylated Nanocarriers for protein and peptide delivery.- Chapter 11. PEGylation of protein and peptides.- Chapter 12. PEGylated nanocarriers for diagnostic applications.- Chapter 13. Multifunctional PEGylated nanocarriers in theragnosis.- Chapter 14. Reversible PEGylation of nanocarriers.- Chapter 15. Stimuli responsive PEGylated Nanocarriers.- Chapter 16. Beyond PEGylation "PEGylation and its alternatives.".- Chapter 17. Current status and Regulatory Aspects of PEGylated Nanoproducts.- Chapter 18. Medicinal and Pharmaceutical Applications of PEGylated Nanocarriers.
