Full Description
This book offers a definitive and comprehensive exploration of precision medicine, capturing both its foundational principles and cutting-edge innovations. Organized into six sections, it guides readers from the basics of individualized healthcare to the advanced application of genomics, epigenomics, pharmacogenomics, and artificial intelligence in cancer treatment. Through detailed cancer-specific chapters—covering gliomas, head & neck cancers, breast, lung, prostate, colon, pancreatic, and other malignancies—the book delivers in-depth insights into molecular profiling, diagnosis, and personalized therapy strategies. Beyond scientific advances, it critically addresses the ethical, clinical, and social dimensions of precision medicine, preparing clinicians, researchers, and policymakers to navigate challenges and harness the future opportunities in this transformative field. By blending scientific rigor with forward-looking perspectives, this volume positions itself as an authoritative reference for oncology researchers, clinicians, bioinformaticians, pharmaceutical scientists, and graduate students seeking to understand and contribute to the future of personalized healthcare.
Contents
Section 1. Introduction to Precision Medicine.- Chapter 1. Basic principles and Concepts.- Chapter 2. Shift from traditional to personalized approaches.- Section 2. Genomics, Epigenomics and Pharmacogenomics.- Chapter 3. Genomics and key alterations.- Chapter 4. Cancer Epigenomics in Precision medicine.- Chapter 5. Pharmacogenomics in personalized treatment.- Chapter 6. Precision Cancer Medicine and Clinical Trial Design.- Chapter 7. Clinical implementation and outcome.- Section 3. Cancer Specific Molecular Profiling, Diagnosis and Treatment.- Chapter 8. Advanced personalized treatment strategies in Glioblastoma.- Chapter 9. Personalized treatment options in Head and Neck Cancer.- Chapter 10. Breast Cancer: Neoantigen vaccines and targeted therapies.- Chapter 11. Personalized therapy in Non-Small Cell Lung Cancer.- Chapter 12. Personalized medicines and prospects in Prostate Cancer.- Chapter 13. Breakthroughs in personalized treatment of Colorectal Cancer.- Chapter 14. Innovative approaches in Pancreatic Cancer treatment.- Chapter 15. Advancements in Hematopoietic Cancers treatment.- Section 4. Nanotherapeutics in Personalized Medicine.- Chapter 16. Targeted delivery for cancer therapy and real-time monitoring using nanotherapeutics.- Chapter 17. Biomarker identification using nanoparticles.- Section 5. Challenges, Limitations and Social considerations.- Chapter 18. Technical and clinical challenges.- Chapter 19. Social issues and Benefits.- Chapter 20. Role of health workers in personalized medicine.- Section 6. Novel Innovations and Future Perspectives.- Chapter 21. Emerging technologies and approaches.- Chapter 22. Application of bioinformatics and computational biology.- Chapter 23. Artificial intelligence (AI) and machine learning (ML) in personalized medicine.- Chapter 24. Potential breakthroughs and future research directions.
