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Full Description
The book offers a timely and comprehensive overview of how oxidative stress influences chronic disease onset, progression, and management. A balanced view of antioxidants and their protective and potentially harmful effects is presented in this book, which combines cutting-edge biochemical research with practical health applications. A review of mechanisms that regulate cellular health, immune function, and disease resistance is presented in this book. The book focuses on key antioxidative enzymes and redox biology. The book covers topics such as the interactions between reactive oxygen, nitrogen, and sulfur species, as well as the therapeutic use of natural antioxidants. There will be valuable insights to be gained by readers into: (i) The role that oxidative stress plays in the development of chronic diseases like cardiovascular disorders, neurodegenerative disorders, and metabolic syndromes. (ii) In terms of their molecular mechanism and biological impact, antioxidants and prooxidants play important roles. (iii) In the fields of food, cosmetics, and medicine, natural product pharmacology, antioxidant delivery systems, and redox-active formulations are of particular interest.
For these reasons, the book starts by pointing out that chronic diseases are becoming a global burden and that a deeper understanding of their molecular basis is urgently needed. A key goal of this book is to bridge the gap between fundamental research and clinical applications by providing an overview of recent advances in mechanisms, biomarkers, and therapeutic strategies for oxidative stress. A valuable resource for biotechnologists, biochemists, biomedical sciences and healthcare professionals working in biochemistry, pharmacology, nutrition and natural product chemistry and doctoral students who wish to understand and address the complex interactions between oxidative stress and chronic diseases, this book can be of great assistance to them.
Contents
1. Mechanisms of antioxidants and prooxidants modulate redox reactions in biological systems.- 2. A better understanding of antioxidant mechanisms in living systems.- 3. Oxidative stress and pathophysiology of chronic diseases.- 4. Plants, microbes, and animals have different antioxidant metabolisms and their applications..- 5. Reactive species, such as ROS, RNS, and RSS.- 6. A review of redox-active natural products, their synthesis, isolation, and biological activities.- 7. Role of antioxidative agents in preventing various chronic diseases, including COVID.- 8. Therapeutics of recombinant enzymes in the management of oxidative stress in vitro and in vivo evaluation of antioxidant capacity.- 9. Health and disease related to natural and synthetic antioxidants in plants, animals, and humans.- 10. Developing innovative techniques for antioxidant delivery and protocols for extracting, isolating, and characterizing new natural antioxidants.- 11. An overview of natural antioxidant pharmacodynamics and pharmacokinetics.- 12. Catalysis of biological redox reactions, likely supplements, subproducts, and dietary antioxidants.- 13. Food, fodder, and cosmetic formulations with safe antioxidant preservatives.



