Full Description
The singular life threatening emergency that a fertility physician encounters in clinical practice is OHSS. Published data indicate a significant increase in OHSS globally. The occurrence of approximately three maternal deaths per 100,000 stimulated women has been reported, and extrapolation of these figures to a global situation would give an impressive number. If ovarian stimulation is performed accordingly to new strategies available, the occurrence of OHSS will be eradicated.The syndrome can be erased by applying ovarian stimulation using the combination of GnRH antagonist with GnRH agonist to trigger ovulation. In this case, the strategy is to freeze all of the oocytes or embryos for later use. This book describes in detail current knowledge to have an OHSS-free clinical practice.
Contents
1. Pathophysiology of OHSS - Is it always iatrogenic?.- 2. Current concepts, etiopathology & staging of OHSS.- 3. Prediction & risk-factors of OHSS.- 4. Primary & Secondary OHSS.- 5. Role of counseling in an OHSS-free clinic.- 6. Role of ovarian markers in prevention of OHSS.- 7. Can newer biochemical markers prevent OHSS?.- 8. Role of ultrasound in the prediction & prevention of OHSS.- 9. Current status of metformin in OHSS prevention.- 10. Tweaking follicular phase stimulation protocols for prevention of OHSS.- 11. Luteal phase strategies to prevent OHSS.- 12. Interventional rescue strategies for unexpected OHSS.- 13. Is HCG trigger history?.- 14. The Role of Ultrasound in minimizing morbidity in OHSS.- 15. Is IVM still relevant for an OHSS free clinic?.-16. Newer drugs, interventions & strategies for an OHSS.- 17. Freeze-all for all is the way ahead.- 18. Is there an ideal stimulation protocol for an OHSS-free clinic?.
