Full Description
This Book is the 4th and final volume of the series under the title, "Introduction to Basics of Pharmacology and Toxicology" - with a primary focus on clinical pharmacology and therapeutics aspects. The initial and major part of this volume provides an extensive description of the use of drugs in clinical practice - with a clear and accessible overview of all the key prescribing topics needed for clinicians and researchers involved in the pharmacology segment. Emphasizing the safe and effective administration of drugs, this volume helps readers understand the principles of clinical pharmacology to prevent medication errors.
This title is also intended for researchers involved in clinical trials and developing a protocol. It is highly significant for practitioners who must critically analyze the literature of published clinical trials and assess the benefits of each trial, as well as its implications for patient care and treatment. A chapter on clinical trial ethics has been included and presented in a well-organized and sequential manner. Problems related to drug use in paediatrics, geriatric, and perinatal pharmacology have also been introduced as separate chapters. Researchers are introduced to the regulatory framework and the critical guidelines they must follow to meet agency approval standards. Full of numerous examples and the latest drug regulation guidelines, makes this volume a must have resource for all early, mid-career and senior clinicians as well as researchers. This is a highly informative and carefully presented book, providing scientific insights for scholars with an interest in clinical pharmacology.
Contents
1. Clinical Pharmacokinetics.- 2. Essential medicines and rational use of drugs.- 3. Drug Information Centre.- 4. Evidence-Based Medicine.- 5. Medication Adherence.- 6. Therapeutic Drug Monitoring.- 7. Medication Error.- 8. Drug use in pregnancy and lactation (Perinatal pharmacology) .- 9. Pediatric Pharmacology.- 10. Geriatric Pharmacology.- 11. Usage of drugs in various Pathological States.- 12. High throughput screening and computer-aided drug designing.- 13. Phase 0 Clinical Trials.- 14. Phase 1 Clinical Trials.- 15. Phase 2 Clinical Trials.- 16. Phase 3 Clinical Trials.- 17. Phase 4 Clinical trials.- 18. Ethics in Clinical Trials.- 19. Vaccine Clinical Trials.- 20. Real-World Evidence Studies and Pragmatic Clinical Trials.- 21. Contract Research Organizations - Roles & Responsibilities.- 22. Bioavailability and Bioequivalence Studies.- 23. New Drugs and Clinical trial rules 2019.- 24. Regulation of healthcare products by the United States Food and Drug Administration and Health Canada.- 25. Regulation of healthcare products by the United States Food and Drug Administration and Health Canada.- 26. Medical Device and Medical Device Regulations.- 27. Off-Label Use of Drugs.- 28. Nonclinical testing methods to assess safety and efficacy of new drugs.- 29. Novel Chemical and Biological Entities in the Past Five Years.- 30. Drug Repurposing.- 31. Specialized Drug Delivery System .- 32. Biologicals and Biosimilars.
