Full Description
This book provides a core understanding of the COVID-19 disease through ultrastructural imaging, using light microscopy, immunofluorescence, and scanning and transmission electron microscopy of samples from COVID-19 patients at different stages of the disease. It provides direct evidence of the impact of the SARS-CoV-2 virus on the cellular level in different age groups, disease stages, and comorbidities. The book explores advanced imaging techniques to enhance understanding of ultrastructural changes and provides a comprehensive overview of SARS-CoV-2-induced ultrastructural alterations in various respiratory tract cells. It summarizes key ultrastructural findings observed in SARS-CoV-2-infected cells, highlighting morphological and subcellular modifications, and features high-resolution images to illustrate virus-induced structural changes effectively.
The book includes contributions from academicians, scientists, and emerging researchers, ensuring an accessible yet in-depth presentation of the subject, and is a useful tool for everyone interested in understanding COVID-19.
Contents
1. SARS-CoV-2 and COVID-19: An Ultrastructural Perspective 2. Ultrastructural and Molecular Architecture of SARS-CoV-2 3. Tropism of SARS-CoV-2: Microscopic Analysis 4. Impact of SARS-CoV-2 in the Ultrastructure of Keratinized Oral Epithelium 5. Impact of SARS-CoV-2 in the Ultrastructure of Non-Keratinized Oral Epithelium 6. Ultrastructure of Different Cells of the Nasal Cavity of COVID-19 Patients 7. Ultrastructural Alteration of Ciliated Epithelium of Bronchoalveolar Lavage Fluids 8. Ultrastructural Variation of Type II Pneumocytes of BALF of COVID-19 Patients 9. Ultrastructural Modification of Alveolar Macrophage of BALF 10. Ultrastructure of Lung-Infiltrated Neutrophils 11. Ultrastructural Modification of Eosinophils in BALF of SARS-CoV-2 Patients 12. Ultrastructural Proof of SARS-CoV-2 Infection in Lymphocytes 13. Ultrastructural Modification of Anucleated Granulocytes in BALF 14. SARS-CoV-2-Induced Formation of Single and Heterotypic Syncytial Cells: An Ultrastructural Confirmation 15. Ultrastructural Evidence for the Impact of Prophylactic Hydroxychloroquine on Impairment and Cellular SARS-CoV-2 Infection in Different Cells of BALF of COVID-19 Patients 16. SARS-CoV-2-Induced Ultrastructural Changes in the Ciliated Epithelium, Type II Pneumocytes, Macrophages, and Neutrophils of COVID-19 Patients 17. Abnormal Ultrastructure Features on Type II Pneumocytes of COVID-19 Patients with Aplastic Anemia
