Full Description
The pace and sophistication of advances in medicine in the past two decades have necessitated a growing need for a comprehensive reference that highlights current issues in medicine. Each volume in the Current Issues in Medicine series is a stand-alone text that provides a broad survey of various critical topics—all accomplished in a user-friendly yet interconnected format. The series not only highlights current advances but also explores related topics such as translational medicine, regulatory science, neglected diseases, global pandemics, patent law, immunotoxicology, theranostics, big data, artificial intelligence, novel imaging tools, combination drug products, and novel therapies. While bridging the gap between basic research and clinical medicine, this series provides a thorough understanding of medicine's potential to address health problems from both the patient's and the provider's perspectives in a healthcare setting. The range of topics covered and the expertise of the contributing authors accurately reflect the rapidly evolving areas within medicine—from basic medical sciences to clinical specialties. Each volume is essential reading for physicians, medical students, nurses, fellows, residents, undergraduate and graduate students, educators, policymakers, and biomedical researchers. The multidisciplinary approach of the series makes it a valuable reference resource for the pharmaceutical industry, academia, and governments. However, unlike other series on medicine or medical textbooks, this series focuses on current trends, perspectives, and issues in medicine that are central to healthcare delivery in the 21st century. Volume 1 focuses on the current issues in basic medical sciences, subjects that are fundamental to the practice of medicine. Specifically, it covers medical biochemistry, genomics, physiology, and pathology. These subjects, traditionally taught in the first two years of medical school that precede clinical instruction, provide a core of basic knowledge critical to the success in clinical medicine during rotations, training, and medical practice.
Contents
1. The Age of COVID-19: Medical Facts and Fiction Section 1: Medical Biochemistry and Genomics 2. Role of Engineered Proteins as Therapeutic Formulations 3. How Physical and Chemical Information Predicts the Action of Molecules: A Historical Overview 4. Three-Dimensional Chromatin in Infectious Disease: A Role for Gene Regulation and Pathogenicity? 5. Aptamers, the Nucleic Acid Antibodies, in Cancer Therapy 6. Identifying Genetic Markers Associated with Susceptibility to Cardiovascular Diseases 7. Production and Application of Multicistronic Constructs for Various Human Disease Therapies 8. The Nuclear Lamina: Protein Accumulation and Disease 9. The Importance of Protein Post-Translational Modifications in the Pathogenesis and Progression of Neurodegenerative Diseases 10. DNA Damage/Repair Management in Cancers 11. Advancing Clinical Cohort Selection with Genomics Analysis on a Distributed Platform 12. Pharmacogenomics of Tamoxifen 13. Nanocrystals: The Universal Formulation Principle to Improve the Bioactivity of Poorly Soluble Actives 14. Cellular Mechanisms of Human Atherogenesis: Focus on Chronification of Inflammation and Mitochondrial Mutations 15. Vitamin D Pathway and the Pathogenesis of Inflammatory Bowel Disease 16. The Structural Ensemble of the Conjugative F-like T4SS 17. Polygenic Risk-Tailored Screening for Prostate Cancer: A Benefit-Harm and Cost-Effectiveness Modelling Study 18. Apoptotic Bodies: Particular Extracellular Vesicles Involved in
Intercellular Communication Section 2: Human Physiology and Pathology 19. Circulating Tumor Cells and Personalized Medicine 20. Pathology in the Era of Personalized Medicine 21. Speech Intelligibility during Clinical and Low Frequency 22. Physiological Renormalization Using Systems Therapeutics 23. Pathology Is Always Around Us: Apophenia in Pathology, a Remarkable Unreported Phenomenon 24. The Secrets of the Mediterranean Diet. Does [Only] Olive Oil Matter? 25. Relationship between Diet, Microbiota, and Healthy Aging 26. Does Low-Density Lipoprotein Cholesterol Induce Inflammation? If So, Does It Matter? Current Insights and Future Perspectives for Novel Therapies 27. Role of Biomarkers in Clinical Development of Cancer Therapies 28. In Sickness and Health: Effects of Gut Microbial Metabolites on Human Physiology 29. Current Methodologies Utilized in the Conduct of Randomized Clinical Trials 30. The Prion-Like Phenomenon in Alzheimer's Disease: Evidence of Pathology Transmission in Humans
