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基本説明
Covers a spectrum of topics in the diagnostics and monitoring of viral ailments with an emphasis on the newer technologies in development such as optical fiber and electrochemical immunosensors, reverse genetics, luminescent molecular imprints of neutrophil biomakers and many others.
Full Description
This book illustrates a variety of challenges that bug hunters try to solve. It is an outstanding collection of the insights and expertise of an interdisciplinary group of researchers from all walks of life: virologists, physicians, immunologists, electrochemists, physicists, computer scientists, biotechnologists, epidemiologists, and molecular biologists, all working at the forefront of diagnostics in fields that cross scientific boundaries. Notwithstanding a dire moment as that of the recent Ebola outbreak in West Africa that saddens us all, we must more than ever peregrinate across oceans, and take the fight to them, as these invisible and exotic but deadly enemies know no barriers and constantly invade our lives. The coming epidemics and killer pandemics require us to continuously innovate in areas of prevention, detection, and therapy.
The present volume focuses on creating virus alerts or hand-held detectors to bring to the field during an epidemic, when possible, or tools for the healthcare worker to rapidly diagnose the patient's ailment. The authors describe the conventional cell cultures and molecular biology methodologies, while introducing state-of-the-art multidisciplinary biosensors. This book is not a manual, set of protocols, or a textbook; it is a glimpse into the advances of virus diagnostic research. Included are a variety of topics that encompass world health issues, local folklore such as associating outbreaks with witchcraft, problems in getting healthcare workers to the outbreak areas, and insights in viral diagnostic pitfalls.
Contents
Foreword, Preface, 1. Practical Experience with an Integrated Syndromic Surveillance System in the Medical, Veterinary, Nursing, and Emergency Respons, 2. Environmental Surveillance for Polioviruses in Israel: Bioerror, Bioterror, or just Mother Nature,. 3. Filoviruses: Deadly Pathogens and Potential Bioweapons, 4. Bridging Diagnostics Research, Development, and Commercialization: Diagnostics for the Developing World, 5. Oropouche Fever: An Overview of the Epidemiological and Molecular Aspects in the Brazilian Amazon Region, 6. Is Avian Influenza Subtype H5N1 a Cause for Concern? A Critical Analysis, 7. Diagnostics of Viral Respiratory Diseases, 8. Reverse Genetics as a Tool for Detection of Negative-Stranded RNA Viruses, 9. Diagnostics of Ebola Hemorrhagic Fever Virus, 10. Pathogen Detection Using Spatially Focused Microwaves and Metal-Enhanced Fluorescence, 11. Lyssavirus Surveillance and Diagnostics: Focus on Africa, 12. Detection of Human Pathogens under Basic Laboratory Conditions by DNA Hybridization Arrays, 13. Differentiation between Viral and Bacterial Respiratory Infections Using Chemiluminescence of Polymorphonuclear Leukocytes, 14. Phage Display for Viral Diagnostics, 15. Nanolithography and Biochips' Role in Viral Detection, 16. Optical Fiber Immunosensors and Genosensors for the Detection of Viruses, 17. Aptamers, a New Class of Binders, with Particular Focus on Diagnostics and Bioactivity in the Field of Virology, 18. Pseudotyped Viruses: A New Sero-Diagnostic Tool, 19. Nucleic Acid Isothermal Amplification Technologies and Point-of-Care Diagnostics, 20. Recent Ebola and Marburg Viral Hemorrhagic Fever Outbreaks in Uganda: The Need for Quick, Reliable Diagnostic Tests, 21. Amperometric Immunoand DNA Sensors for Rapid and Specific Identification of Viruses
