Full Description
This book provides a comprehensive overview of the use of noble metal nanoparticles for bioimaging and biosensing. It starts with a review on the synthesis, characterization, optical properties, and bioconjugation of noble metal nanoparticles, followed by introduction of various biodetection techniques based on noble metal nanoparticles. In between these topics, microfabrication of biosensing chips and the use of microfluidics to enhance biosensing performance are discussed.
Contents
Synthesis, characterization, and optical properties of noble metal nanoparticles. Bioconjugation of noble metal nanoparticles and their applications to biolabeling and bioimaging. Colorimetric bioassays using noble metal nanoparticles. Slide- and microarray-based biosensors using noble metal nanoparticles. Optical waveguide-based biosensors using noble metal nanoparticles. Fabrication of biosensing chips. Microfluidics for biosensing chips. Biodetection based on resonance light-scattering of noble metal nanoparticles. Photoluminescence of gold nanoparticles and their applications to sensing and cell imaging. Biodetection based on fluorescence quenching and surface-enhanced fluorescence using noble metal nanoparticles. Surface-enhanced Raman scattering based on noble metal nanoparticles. Mass spectrometric bioanalysis assisted by noble metal nanoparticles.