Full Description
This book summarizes the potent effect of ultraviolet radiation (UVR) on the photoaging and cancer formation. Skin is the largest human organ which continually reconstructs itself to ensure its viability, integrity, and ability to provide protection for the body. This protection can be compromised by the aging of the skin which ultimately promotes skin inflammation, impaired wound repair, and increased risk of skin cancer. The book entails mechanistic insights into the UVR-induced immunomodulation and DNA damage in the skin to delineate the pathogenesis, and develop novel ways for prevention of photoaging of the skin cells. It also elucidates the potential of nanotechnology in the treatment of skin cancer. Further, it discusses the bioinformatics approaches to understand the molecular mechanism of photoaging and cancer formation.
Contents
Chapter 1. Skin anatomy & morphology.- Chapter 2. Cellular & Molecular events: skin aging & cancer.- Chapter 3. Human skin stem cell and aging.- Chapter 4. UV-R induced skin damage: Skin againg & cancer.- Chapter 5. UV-R induced immunomodulation :Skin aging & cancer.- Chapter 6. UV-R and Role of Pigmentation in skin aging & cancer.- Chapter 7. UV-R and Vitamin D synthesis.- Chapter 8. UV-R induced melanin chemi-excitation in melanoma pathogenesis.- Chapter 9. Future prospective of nanotechnology in skin cancer therapeutics.- Chapter 10. Role of bioinformatics in understanding of molecular mechanism and prevention of skin cancer.- Chapter 11. UV-R interaction with skin. Cases of study.- Chapter 12. Monitoring the genotoxic potential of sunlight and DNA photoprotection of sunscreen.
