Full Description
Human adenoviruses play a central role in human diseases and as vectors for vaccines and gene delivery. This monograph describes the underlying principles of adenovirus molecular and structural biology, pathogenesis, antiviral measures and vector development. Much of the history of this virus and the many contributions made by its study are embedded in these discussions. Topics and questions that require further investigation are also considered.Although current virology textbooks cover topics related to adenoviruses, this book provides a comprehensive description of the virus and its interactions with the host. Students and researchers with a particular interest in adenoviruses, gene therapists, and virologists interested in viral pathogenesis will benefit from this book, which presents a unique integration of the basics with applied research in the field.
Contents
A Short History; Structure of Virus Particles; Cell Attachment and Entry; ntracellular Trafficking; Organization and Expression of the Genome; Genome Replication; Assembly and Maturation of Progeny Virus Particles; Pathogenesis; Anti-Viral Defenses; Antivirals; Therapeutic Applications;
