基本説明
New in paperback. Hardcover was published in 2008.
Full Description
This book serves as a treasure for all those who have an interest in nuclear receptor coregulators and human diseases. Written by experts in the field, each chapter provides comprehensive, up-to-date information on the physiologic and pathologic roles of coregulators in specific organ systems, giving biomedical students; basic and clinical researchers; and educators in diverse sub-specialties a thorough summary of the overall subject. Readers will be able to understand the important current information and views on specific coactivators and corepressors and their roles in the pathogenesis of human diseases in areas outside their own expertise or experience. A special emphasis is placed on the "classic" papers as well as perspectives on future directions for the field.
Contents
Coactivators -- Master Genes for Function/Disease; Coregulators as Oncogenes and Tumor Suppressors; Corepressors and Organogenenesis; Coactivators in the Cell Cycle; Coactivators, Methylation, and Cellular Function; RIP140 Corepressor in Energy Metabolism; Coregulators and Proteasome Function; Coactivators in Metabolism; Corepressors in Metabolism; Energy Sensing Cofactors in Metabolism; Coactivators and Inflammation; Coactivators in Liver Function; Coregulators in CNS Function and Disease; Coactivators in the Cardiovascular System; Coactivators in Prostate Cancer; Coregulators in Breast Cancer; Coregulators and Genome-wide Targets; Coregulators in Toxicology; Coregulators and Selective Receptor Drugs.
