Full Description
This book discusses the recent developments in the therapeutic implications of cancer stem cells for the effective diagnosis, prognosis, and treatment of cancer.
It summarizes the various stem cells of common cancers including colon, pancreas, lungs, prostate, melanoma, and glioblastoma, and reviews the potential role of cancer stem cells in tissue aggressiveness, examining the functional contribution of cancer stem cells in the establishment and recurrence of cancerous tumors. Further, it explores the potential of cancer stem cells as novel therapeutic targets for the treatment and prevention of tumor progression.
The book also discusses the various approaches for detecting, isolating, and characterizing different cancer stem cells and signaling pathways that control their replication, survival, and differentiation. Lastly, it explores the key features and mechanisms of drug resistance, chemo-resistance, and radio-resistance in cancer stem cells to improve therapeuticrationale.
Contents
Chapter 1. Introduction to cancer stem cells.- Chapter 2. Types of Cancer Stem Cells.- Chapter 3. Isolation and Characterization of Cancer Stem Cells (CSCs).- Chapter 4. Lung and Prostate Cancer Stem Cells.- Chapter 5. A differential role of miRNAs in regulation of breast cancer stem cells.- Chapter 6. Skin stem cells in cancer.- Chapter 7. Ocular Cancer stem cells: Advances in therapeutic interventions.- Chapter 8. Cancer Stem Cells and Tumour Aggressiveness.- Chapter 9. Therapeutic Implication of Cancer Stem Cells.-Chapter 10. Glioblastoma stem cells as a therapeutic target.- Chapter 11. Cancer stem cells and therapeutic angiogenesis.- Chapter 12. Cancer stem cells as a seed for cancer metastasis.- Chapter 13. Functionality of intron specific genes and cancer stem cells in the progression of colorectal cancer.- Chapter 14. Technological advancement in Cancer Stem Cell Research.- Chapter 15. Controversies in Isolationand Characterization of Cancer Stem Cells.- Chapter 16. Targeting therapies for cancer stem cells.- Chapter 17. Targeting Cancer stem cells by nanoenabled drug delivery.- Chapter 18. Cancer Stem Cells in Patients Survival and Therapies in Cancer.-
