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Full Description
This volume reviews the recent advances in formation of C-F bonds and X-F bonds (X = heteroatom) to produce useful fluorinated molecules for pharmaceuticals, materials and more. Reactions and methods associated with fluorination, including monofluorination, difluorination, trifluorination and other polyfluorination that have emerged within the past few years are systematically discussed. With contributions from front-line researchers in this field from both academia and industry, this book provides a valuable resource for scholars, graduate students as well as professionals.
Contents
Monofluorination (synthesis of -CF and XF compounds).- Synthesis of alkyl fluorides.- Synthesis of alkenyl fluorides.- Synthesis of aryl fluorides.- Synthesis of X-F compounds (X = heteroatom).- Difluorination (synthesies of -CF2- and -CF2H compounds).- Trifluorination.- Other polyfluorination [synthesies of -CF3, -CmFn (n > 3) and -XFn compounds].