Full Description
These four volumes comprising "GnRH Analogues in Cancer and Human Reproduction" are a distillation of the presentations of the invited speakers at a landmark International Symposium bearing the same name, organized by one of us (B. L. ) and held in Geneva, Switzerland in February 1988. The Symposium was truly interdisciplinary spanning gonadal hormone dependent disease including various forms of cancer and ranging to control of fertility, both pro- and conception. The international flavor can be caught from the 480 participants and 259 contributors drawn from 14 countries. The Symposium, and therefore this book, would not have been possible without the backing of The International Committee for Research in Reproduction and the sponsorship of the International Society of Gynecologic Endocrinology, The Swiss Society of Fertility and Sterility, The University of Geneva School of Medicine, The Swiss Society of Endocrinology and The US Foundation for Studies in Reproduction Inc. , and help from the World Health Organization. B. H. Vickery B. Lunenfeld June 1989 LIST OF CONTRIBUTORS TO THE SERIES H. Bartermann A. Abbondante First Institute of Obstetrics and Urologische Universitatsklinik Kiel Gynecology Arnold-Heller Strasse 7 University "La Sapienza" D-2300 Kiel 1, FRG Rome,ltaly M. Bartholomew P. Abel Department of Medicine/Endocrinology Department of Urology Milton S. Hershey Medical Center Hammersmith Hospital Pennsylvania State University DuCane Road PO Box 850, Hershey, PA 17033, USA London W12 OHS, UK D. Beck H.
Contents
1 Reversible inhibition of sexual maturation in male rats: a safety evaluation for the use of LHRH analogues in precocious puberty.- 2 Mechanism of action of GnRH analogues in sexual maturation and function.- 3 Should all girls with central precocious puberty be treated by LHRH analogue?.- 4 Long-term experience with a superactive GnRH analogue in the treatment of precocious puberty.- 5 Effects of GnRH analogues on growth and bone maturation: a role for growth factors and adrenal androgens.- 6 Growth patterns and skeletal maturation during sex steroid suppression and reactivation in central precocious puberty.- 7 Precocious puberty: pathophysiology and treatment.- 8 Effects of GnRH agonists on pituitary gonadotropins: dissociated secretion of subunits in children with precocious puberty treated with [D-Trp6]LHRH microcapsules.- 9 Testicular changes in patients treated with buserelin for precocious puberty.- 10 Influence of buserelin on testicular tissue after long-term treatment for precocious puberty and prostatic cancer.- 11 GnRH analogues in the development of a male contraceptive: importance of testosterone substitution and reversibility of pituitary and testicular suppression.- 12 Clinical pharmacology of LHRH antagonists.- 13 Clinical studies with the Nal-Glu GnRH antagonist.- 14 The clinical relevance of bone mass measurements.- 15 Bone calcium dynamics in women with declining estrogen levels.- 16 Effects of GnRH agonist-induced ovarian suppression on calcium homeostasis and bone metabolism in premenopausal women.- 17 GnRH analogs and safety.- 18 Management of post-marketing surveillance following short-and long-term use of GnRH analogues.
