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Full Description
Products from Cells - Cells as Products This book ist he "lasting" product, a resource ofup to date information in the scientific literature fort he field ofanimal cell tec hnology, as it was presented during a pleasant and s timulating mee ting that was held in Lugano Switzerland in April 1999. "Products" appeartwice int he title oft he conference. This clearly indicates the fact that the focus oft he papers presented during this meeting was really the application ofn ew technologies (novel reactors or novel vectors, for example for the preparation and/ort he more efficient generation ofproducts ) that could be used, mainly, int he medical field. Classical approaches forthe use ofa nimal cells, for example forthe p r oduction of virus vaccines for human and animal health, still remain an important technology and still have, surprisingly, quite significant potential for further development and improvement. How ever, it appears that major technological advances an d major growth from an economical point ofview are occurring in other areas.
Most importantly, protein production on the basis of recombinant DNA molecules transferred into a nimal cells, appears to be an ever increasing field of interest and innovation, even though the first production scheme with this technology was approved more than 15 years ago.
Contents
Improvement and Induction of High Productivity.- Metabolic and Process Engineering.- Post-Translational Modifications.- Reactor Design and Operation.- Transient Gene Expression.- Regulatory and Stability Issues in Animal Cell Culture for Pharmaceutical Production.- Novel Therapeutic and Prophylactic Approaches Based on Cells and Nucleic Acids.- Vaccines and Immunologicals.- Cell Characterization, Validation, Safety Adventious Agents.- Animal or Patient Derived Cells and Tissues for Therapeutic Applications.
