Molecular characterization of ESBL producing Klebsiella SPP isolates : ESBLs, Klebsiella spp, Iran （2011. 224 S. 220 mm）

Ghafourian, Sobhan/Z, Sekawi./N, Sadeghifard.

LAP LAMBERT ACADEMIC PUBLISHING（2011発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 224 p.
• 商品コード 9783844317312

Description

(Text)
ESBLs are known as extended-spectrum because they are able to hydrolyze a broader spectrum of beta- lactam antibiotics than the simple parent beta- lactamases from which they are derived. Such ESBLs have also the ability to inactivate beta-lactam antibiotics containing an oxyimino-group such as oxyimino-cephalosporins (eg; ceftazidime, ceftriaxone, cefotaxime) as well as oxyimino- monobactam. Furthermore, they are not active against cephamycins and carbapenems. Generally, they are inhibited by beta-lactamase-inhibitors such as clavulanate and tazobactam. ESBLs have been found in a wide range of Gram-negative rods. However, the vast majority of strains expressing these enzymes belong to the Enterobacteriaceae family. K.pneumoniae remains as the major ESBL-producer.
(Author portrait)
Ghafourian, SobhanSobhan Ghafourian is Researcher in Department of Medical Microbiology, Ilam University of Medical Sciences,Iran.In 2007,He started study in field of Medical microbiology in faculty of medical and health siences,University of Putra Malaysia. His research interests is in bacteriology particularly multi-resistant bacteria.