基本説明
『ISCN 2005』に続く、4年振りの改訂版。人類染色体を研究する技術者、学生に必携のレファレンス。染色体核型記載法に関する常任委員会(ISCN)によりまとめられている。
Recommendations of the International Standing Committee on Human Cytogenetic Nomenclature. Published in collaboration with 'Cytogenetic and Genome Research' Plus fold-out: 'The Normal Human Karyotype G- and R-bands'. Updated the now classic system of human cytogentetic nomenclature prepared by an expert committee and published in collaboration with Cytogenetic and Genome Research (formerly: Cytogenetics and Cell Genetics) since 1963. Revised and finalized by the ISCN Committee and its advisors at a meeting in Vancouver, B.C., in October 2008, the ISCN 2009 updates, revises and incorporates all previous human cytogenetic nomenclature recommendations into one systematically organized publication that supersedes all previous ISCN recommendations.
Full Description
This publication updates the now classic system of human cytogenetic nomenclature prepared by an expert committee and published in collaboration with Cytogenetic and Genome Research (formerly: Cytogenetics and Cell Genetics) since 1963. Revised and finalized by the ISCN Committee and its advisors at a meeting in Vancouver, B.C., in October 2008, the "ISCN 2009" updates, revises and incorporates all previous human cytogenetic nomenclature recommendations into one systematically organized publication that supersedes all previous ISCN recommendations. What is new in "ISCN 2009"?: new idiograms at all band levels have been revised based upon higher-resolution analysis of banded chromosomes; the neoplasia nomenclature has been revised to allow the use of idem or stemline/sideline notation to describe clonal evolution; new examples reflecting unique situations are included in most chapters; the nomenclature for microarray results has been revised to accommodate any platform and provides detailed and short systems of description; a nomenclature for MLPA results has been introduced.
"ISCN 2009" is thus an indispensable reference for human cytogeneticists, technicians and students for the interpretation and communication of human cytogenetic nomenclature.
Contents
Historical Introduction; Normal Chromosomes; Symbols and Abbreviated Terms; Karyotype Designation; Uncertainty in Chromosome or Band Designation; Order of Chromosome Abnormalities in the Karyotype; Normal Variable Chromosome Features; Numerical Chromosome Abnormalities; Structural Chromosome Rearrangements; Chromosome Breakage; Neoplasia; Meiotic Chromosomes; In situ Hybridization; Copy Number Detection.
