基本説明
Reprint of: 'Cytogenetic and Genome Research 2004, Vol. 107, No. 3-4'.
Full Description
This volume offers an extensive array of reviews on the roles of DNA repair proteins in meiotic recombination. The use of various organisms serves to underscore the marked degree of conservation of these processes among sexually reproducing organisms, but also highlights more subtle species-specific adaptations to meiotic recombination. Contributed by leaders in the field, each chapter reflects the current state of their research and also provides a forum for new ideas and concepts in meiotic recombination. By focussing on different pathways involved in meiosis and recombination, this volume highlights the complexity of these processes and demonstrates how much has been learned in recent years as a result of the multiple approaches to studying these events in various model organisms. Geneticists, cytogeneticists, developmental biologists, and those involved in research on infertility and germ cell biology will find much to interest them in this outstanding collection of reviews.
Contents
Mismatch repair proteins: key regulators of genetic recombination: Surtees JA, Argueso JL, Alani E Studies on crossover-specific mutants and the distribution of cross ing over in Drosophila females: Bhagat R, Manheim EA, Sherizen DE, McKim KS Unique invasions and resolutions: DNA repair proteins in meiotic re combination in Drosophila melanogaster: Blanton H, Sekelsky J A role for the MutL homologue MLH2 in controlling heteroduplex form ation and in regulating between two different crossover pathways in budding yeast: Abdullah MFF, Hoffmann ER, Cotton VE, Borts RH Homologous recombinational repair proteins in mouse meiosis: Bannis ter LA, Schimenti JC Roles of RecA homologues Rad51 and Dmc1 during meiotic recombinatio n: Shinohara A, Shinohara M Inter-sex variation in synaptonemal complex lengths largely determi ne the different recombination rates in male and female germ cells: Tease C, Hulten MA Novel and diverse functions of the DNA mismatch repair family in ma mmalian meiosis and recombination: Kolas NK, Cohen PE Meiotic recombination intermediates and mismatch repair proteins: H offmann ER, Borts RH Cytological studies of meiotic recombination in human males: Hassol d T, Judis L, Chan ER, Schwartz S, Seftel A, Lynn A The mammalian mid-pachytene checkpoint: meiotic arrest in spermatoc ytes with a mutation in Atm alone or in combination with a Trp53 (p 53) or Cdkn1a (p21/cip1) mutation: Ashley T, Westphal C, Plug-de Ma ggio A, de Rooij DG Author Index
