Bipolar Depression : Molecular Neurobiology, Clinical Diagnosis and Pharmacotherapy (Milestones in Drug Therapy)

Zarate, C. A. (EDT)/ Manji, H. K. (EDT)

Birkhäuser（2008/08発売）

• 製本 Hardcover:ハードカバー版／ページ数 250 p.
• 商品コード 9783764385668

Full Description

Although our knowledge of mood disorders is expanding, comparatively little is known about bipolar depression in particular. This book offers the most up-to-date information about the diagnosis, treatment, and research surrounding bipolar depression. Early chapters provide diagnostic information and review the course, outcome and genetics of this heritable condition. The book gives a thorough and unique overview of the neurobiology of the disorder, including neuroimaging work. Several chapters delineate the treatment of bipolar depression in special populations such as children and pregnant women. Furthermore, the particular issues of suicide, focusing on the need for assessment during both acute and maintenance treatment, are addressed. Finally, acute and long-term treatment strategies for bipolar depression are discussed, including both traditional and novel therapeutics, as well as non-pharmacological treatments. This volume offers researchers and clinicians key insights into this devastating disorder.

Contents

Bipolar depression: Clinical phenotype and course of illness.- The history of bipolar disorders.- The clinical diagnosis of bipolar depression.- Course and outcome of bipolar disorder - focusing on depressive aspects.- Suicide and bipolar disorder.- Bipolar depression: Neurobiology.- The genetic basis of bipolar disorder.- Understanding the neurobiology of bipolar depression.- Non-pharmacological treatments and chronobiological aspects of bipolar disorder: implications for novel therapeutics.- Neuroimaging studies of bipolar depression: therapeutic implications.- Acute and long-term treatment of bipolar disorder.- Pharmacological treatment of acute bipolar depression.- Pharmacological treatment of the maintenance phase of bipolar depression: focus on relapse prevention studies and the impact of design on generalizability.- Non-pharmacological somatic treatments for bipolar depression.- Potential novel treatments for bipolar depression.- Treatment of bipolar disorder in special populations.- Late-onset bipolar disorder.- Treatment of childhood-onset bipolar disorder.- Treatment of bipolar disorder during and after pregnancy.- Conclusion.