Inflammatory Cardiomyopathy (DCMi) - Pathogenesis and Therapy (Progress in Inflammation Research)

Schultheiß, H. (EDT)/ Noutsias, M. (EDT)

Birkhäuser（2008/08発売）

• 製本 Hardcover:ハードカバー版／ページ数 300 p.
• 商品コード 9783764383510

Full Description

Cardiomyopathy is one of the most frequent causes of heart failure. It is often associated with inadequate heart pumping or other heart function abnormalities. There are many different causes of the disease, e.g. other diseases, alcoholism, high blood pressure, viral infections; therefore many different kinds of cardiomyopathies exist, belonging to five main types of CM: Dilated CM, Hypertrophic CM, Restrictive CM, Right Ventricular CM, Nonclassifiable CM. This volume focuses on inflammatory CM, belonging to the Dilated Cardiomyopathies (DCMi). It covers epidemiology/prognosis, pathology, immunology, diagnosis and treatment strategies.

Contents

Myocarditis and inflammatory cardiomyopathy — clinical management, epidemiology and prognosis.- Pathogenesis, diagnosis and treatment of pericarditis.- Epidemiology and Prognosis of Myocarditis and dilated Cardiomyopathy: Predictive Value of Clinical Parameters and Biopsy Findings.- Animal models of myocarditis — autoimmunity and viral infection; therapeutic interventions.- Autoimmune Murine Myocarditis and Immunomodulatory Interventions.- Coxsackievirus-induced murine myocarditis and immunomodulatory interventions.- Myocardial Proteases and Matrix Remodeling in Acute Myocarditis and Inflammatory Cardiomyopathy.- Alterations of the immune system in human viral and inflammatory cardiomyopathy.- Molecular genetics of cardiomyopathies and myocarditis.- Pathogenic relevance of autoantibodies in dilated cardiomyopathy.- The role of cytokines in inflammation-induced cardiomyopathy: Pathogenesis and therapeutic implications.- Diagnosis of inflammatory and viral cardiomyopathy.- Histology and immunohistology of myocarditis.- Immunohistological diagnosis of inflammatory cardiomyopathy and diagnosis of cardiotropic viral infections.- Cardiac magnetic resonance imaging: A non-invasive approach for the detection of myocardial inflammation — Potentials and limitations.- Treatment strategies in inflammatory cardiomyopathy patients.- Clinical management of acute myocarditis and cardiomyopathy.- Immunosuppressive treatment of inflammatory cardiomyopathy patients.- Antiviral interferon-? treatment in patients with chronic viral cardiomyopathy.- Immunoadsorption in dilated cardiomyopathy patients.