- ホーム
- > 洋書
- > 英文書
- > Science / Mathematics
Full Description
During the 1980s and 1990s, ecotoxicology has established its place as an interdisciplinary science concerned about the effects of chemicals on populations and ecosystems, thus bridging the gap between biological and environmental sciences, ecology, chemistry and traditional toxicology. In modern ecotoxicology, fish have become the major vertebrate model. This volume summarizes present knowledge in several fields of primary ecotoxicological interest, ranging from the use of (ultra)structural modifications of selected cell systems as sources of biomarkers for environmental impact, to monitoring the impact of xenobiotics in fish. Also examined are: the importance of early life-stage tests with fish; the bioaccumulation of xenobiotics in fish; the origin of liver neoplastic lesions in small fish species; immunocytochemical approaches to monitoring effects in sytochrome P450-related biotransformation; the impact of heavy metals in soft water systems; the environmental toxicology of organotin compounds; oxidative stress in fish by environmental pollutants; and effects by oestrogenic substances in aquatic systems.
Contents
Fish cell lines as a tool in aquatic toxicology, Helmut Segner; primary cell cultures from fish in ecotoxicology, Gilles Monod et al; cytological alterations in fish hepatocytes In Vivo and In Vitro sublethal exposure to xenobiotics - structural biomarkers of environmental contamination, Thomas Braunbeck; architectural pattern, tissue and cellular morphology in livers of fishes - relationships to experimentally-induced neoplastic responses, David E. Hinton, John A. Couch; immunochemical approaches to studies of CYPIA localization and induction of xenobiotics in fish, Anders Goksoyr, Astrid-Mette Husoy; oxidative stress in fish by environmental pollutants, Reinhard Lackner; origin of cadmium and lead in clear softwater lakes of high-altitude and high-latitude, and their bioavailability and toxicity to fish, Gunter Kock, Rudolf Hofer; effects of organotin compounds in fish - from the molecular to the population level, Karl Fent; multiple stressors in the Sacramento watershed, David E. Hinton; effects of oestrogenic substances in the aquatic environment, Peter Matthiessen, John P. Sumpter; testing of chemicals with fish - a critical evaluation of tests with special regard to zebrafish, Roland Nagel, Karla Isberner; bioaccumulation of xenobiotics in fish, Bruno Streit.
