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Description
(Text)
Excessive weight gain is associated with metabolic and hormonal changes that predispose cats to insulin resistance and other disorders. The adipokine leptin is an important regulator of energy metabolism, and circulating leptin concentrations correlate with fat mass in cats and other species. In cats, leptin is associated with insulin resistance, independent of bodyweight. Although dietary factors such as energy density, fat content and feeding pattern increase the risk of obesity, there is limited information on how dietary factors such as feeding, fasting, and macronutrient content influence leptin concentrations in cats. The aims of this study were to compare leptin concentrations in lean healthy cats fed diets high in protein, fat and carbohydrate, to assess associations between leptin concentrations and insulin, glucose, and NEFA concentrations, and to determine the effects of feeding pattern on baseline and postprandial leptin.
(Author portrait)
Tarkosová, Dagmar
Dr. Dagmar Tarkosová - Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences BRNO.
