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Odnoy iz glavnykh prichin, sderzhivayushchikh primenenie gadoliniya dlya neytron-zakhvatyvayushchey terapii, yavlyaetsya ego toksichnost'. Dlya uspeshnoy NZT neobkhodimo obespechit' vysokuyu kontsentratsiyu gadoliniya v tkani opukholi v techenie dlitel'nogo perioda oblucheniya, a takzhe bezopasnost' ego primeneniya. Idei ispol'zovaniya magnitnykh nanochastits dlya povysheniya klinicheskoy effektivnosti lekarstv osnovany na tom, chto veshchestva, sozdannye s pomoshch'yu nanotekhnologicheskikh podkhodov, otlichayutsya po svoim fiziko-khimicheskim svoystvam ot soedineniy, poluchennykh v traditsionnoy lekarstvennoy forme. Magnitnye nanochastitsy mozhno pozitsionirovat' s pomoshch'yu magnitnogo polya, a takzhe beskontaktno upravlyat' ikh peremeshcheniem v organakh i tkanyakh za schet vozdeystviya vneshnego magnitnogo polya. Kletki-fagotsity transportiruyut magnitnye nanochastitsy v "tkani-misheni", a magnitnoe pole dopolnitel'no fokusiruet i lokalizuet zonu terapevticheskogo vozdeystviya. Avtorom razrabotan novyy stabil'nyy metallorganicheskiy material. Kombinatsiya razmera nanochastits, kontsentratsii gadoliniya vnutri etikh chastits i magnitnykh svoystv delaet ego ves'ma perspektivnym kachestve nositelya gadoliniya dlya Gd-NZT.