Predicting Transcription Factor Complexes : A Novel Approach to Data Integration in Systems Biology (Bestmasters) （2015）

Will, Thorsten

Springer Spektrum（2014/12発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 142 p.
• 商品コード 9783658082680

Full Description

In his master thesis Thorsten Will proposes the substantial information content of protein complexes involving transcription factors in the context of gene regulatory networks, designs the first computational approaches to predict such complexes as well as their regulatory function and verifies the practicability using data of the well-studied yeast S.cereviseae. The novel insights offer extensive capabilities towards a better understanding of the combinatorial control driving transcriptional regulation.

Contents

Protein Complex Prediction.- Protein-Protein Interaction Networks.- Domain-Domain Interaction Networks.- Combinatorial Algorithms.- Algorithm Engineering.