Description
(Table of content)
Section I Amphetamine and Psychologen Dependence.- 1 General Pharmacology of Amphetamine-Like Drugs.- 2 Amphetamine Dependence; Clinical Features.- 3 Pharmacology and Classification of LSD-like Hallucinogens.- Section II Marihuana Dependence.- 1 Cannabis. Its Chemistry, Pharmacology, and Toxicology.- Autor Index.l Transmission.- I. Biochemical Neuropharmacology.- 1. Adrenergic Transmission.- a) Storage of CA.- b) Uptake of CA.- c) Release of CA.- d) Enzymatic Inactivation of CA.- e) Synthesis of CA.- f) Turnover of CA.- g) Uptake into and Release from Adrenergically Innervated Tissues of Amphetamine Itself.- h) Amphetamine Metabolites and Tissue CA.- i) Summary and Conclusions.- 2. Serotoninergic (5HT) Transmission.- a) Storage of 5HT.- b) Uptake of 5HT into Neurons and Platelets.- c) Release of 5HT.- d) Enzymatic Inactivation of 5HT.- e) Synthesis and Turnover of Brain 5HT.- f) Summary and Conclusions.- 3. Cholinergic Transmission.- 4. Other Putative Transmittors.- 5. Secondary Transmission; Cyclic Adenosine-3?,5?-monophosphate (cAMP).- 6. Summary and Conclusions.- II. Functional Neuropharmacology.- 1. Effects of Amphetamine on Peripheral Noradrenergically Innervated and Other Tissues in Vivo and in Vitro.- a) The Cat Nictitating Membrane and the Rat Inferior Eyelid.- b) The Cat Iris.- c) The Guinea Pig Vas Deferens.- d) The Rabbit and Guinea Pig Intestines.- e) The Guinea Pig Bladder.- f) Other Peripheral Effects of Amphetamine Possibly Mediated via Serotoninergic Mechanisms.- g) On Tachyphylaxis to the Sympathomimetic Effects of Amphetamine and its Metabolites.- h) Summary of Conclusions.- 2. Effect of Amphetamine on Sympathetic Ganglia.- 3. Effects of Amphetamine on the Nerve Impulse Activity of Single Neurons in the Central Nervous System.- a) Brain Stem Reticular Formation.- b) Hypothalamus.- c) Locus Ceruleus.- d) Substantia Nigra.- e) Caudate Nucleus.- f) Raphé Nuclei.- g) Summary and Conclusions.- 4. Functional Effects of Amphetamine Directly Related to Release of DA, NA, and 5HT in the CNS.- a) Amphetamine Induced Turning and Rotation in Rats and Mice after Unilateral Lesions in the Dopamine Neuronal Systems.- b) The Flexor Reflex.- c) The Extensor Reflex.- d) Summary and Conclusions.- 5. General Summary and Conclusions.- C. Pharmacologic Effects of Amphetamine.- I. Behavioral Effects of Amphetamine.- 1. Gross Behavior.- a) Stereotyped Behavior.- b) Motor Activity.- c) Behavior Observed in the Open Field.- d) Exploratory Behavior.- e) Gross Behavior Effects in Birds.- f) General Summary and Conclusions.- 2. Social Behaviors.- a) Social Interaction.- b) Aggressive Behavior.- c) Sexual Behavior.- 3. Conditioned and Operant Behaviors.- a) The Conditioned Avoidance Response.- b) Positively Reinforced Operant Behavior.- c) Intracranial Self-Stimulation.- d) Self-Administration of Amphetamine in Animals.- e) Amphetamine as an Aversive Stimulus.- f) Maze Performance.- g) Conditioned Reflexes.- h) Miscellaneous Behavioral Studies.- 4. Effects of Amphetamine on Learning and Memory.- a) Experiments on Learning and Memory.- b) State-Dependent Learning.- c) Summary and Conclusions.- II. Effects of Amphetamine on Food and Water Intake.- 1. Food Intake.- a) Amphetamine-Induced Anorexia.- b) Effects of Other Drugs on Amphetamine-Induced Anorexia.- c) Effects o
Contents
Section I Amphetamine and Psychologen Dependence.- 1 General Pharmacology of Amphetamine-Like Drugs.- 2 Amphetamine Dependence; Clinical Features.- 3 Pharmacology and Classification of LSD-like Hallucinogens.- Section II Marihuana Dependence.- 1 Cannabis. Its Chemistry, Pharmacology, and Toxicology.- Autor Index.
