Full Description
Clinical studies during the past 10 years have shown that PET is more sensitive than CT and MRI for the detection of many tumors. In many cases, however, for example in head and neck tumors, combination with radiological procedures is necessary. It may be speculated that PET should be the first study in a malignant tumor when metastatic spread is suspected. MRI and CT may then be restricted to those body areas which evince sites of increased glucose metabolism. Thus, a combination of metabolic and morphologic procedures will enhance tumor detection and change the therapeutic strategy. In this light, an atlas including PET, CT, MRI, and histology data seems desirable to combine metabolic and morphologic imaging. This book presents an overview of the available data which should be of great interest not only for specialists in radiology and nuclear medicine, but also for oncologists.
Contents
1 Introduction.- 2 Principles of Positron Emission Tomography.- 2.1 F-18 Fluorodeoxyglucose(FDG).- 2.2 Principles of Measurement.- References.- 3 Normal Findings.- 3.1 Technique.- 3.2 Qualitative Image Assessment.- 4 Cancer of the Head and Neck.- 4.1 Primary Tumor.- 4.2 Lymph Node Metastases.- 4.3 Recurrence.- 4.4 Distant Metastases.- 4.5 Pitfalls.- 5 Malignant Melanoma.- 5.1 In Transit and Limited Nodal Metastases (AJCC Stage III).- 5.2 Distant metastases (AJCC Stage IV).- 5.3 Pitfalls.- References.- 6 Colorectal Cancer.- 6.1 Sensitivity and Specificity of PET vs. CT.- 6.2 Preoperative Staging of Recurrent Tumor.- 6.3 Diagnosis of Recurrent Tumor.- 6.4 Preoperative Staging of Primary Tumor.- 6.5 Indications for PET Imaging.- 6.6 Technical Issues.- References.- 7 Thyroid Cancer.- 7.1 Primary Tumor/Preoperative Staging.- 7.2 Differentiated Thyroid Cancer.- 7.3 Medullary Thyroid Cancer.- References.- 8 Non-Small Cell Lung Cancer.- 8.1 PET Imaging Protocols Used in This Chapter.- 8.2 Primary Tumor.- 8.3 Local Recurrence.- 8.4 Lymph Node Metastases.- 8.5 Distant Metastases.- 8.6 Variants and Pitfalls.- 9 Breast Cancer.- 9.1 Primary Tumor.- 9.2 Local Recurrence.- 9.3 Axillary Lymph Node Metastases.- 9.4 Distant Metastases.- 10 Testicular Germ Cell Tumors.- 11 Malignant Lymphomas.- 11.1 Nodal Disease.- 11.2 Extranodal Disease.- 11.3 Lymphoma Relapse.- 11.4 Therapy Control.- 11.5 Variants and Pitfalls.- 12 Pancreatic Lesions.- 12.1 Ductal Adenocarcinoma.- 12.2 Other Malignant Tumors.- 12.3 Metastases.- 12.4 Chronic Pancreatitis.- 12.5 Pitfalls.- References.- 13 Brain Tumors.- 13.1 PET Imaging Protocol Used in This Chapter.- 13.2 Primary Tumor: High Grade.- 13.3 Primary Tumor: Low Grade.- 13.4 Primary Tumor: Others.- 13.5 Intracranial Metastases.- References.- 14 GynecologicalTumors (Except Breast Cancer).
