Full Description
Practically all the chapters in this volume present. It is possible that the cerebral contain new and previously unpublished system has a neurotransmitter role, espe- research reports and reviews on the phys- cially as intracerebral angiotensin-induced iological mechanisms which induce drink- drinking seems to depend on catecholami- ing of non-nutritive fluids. Though based nergic, perhaps dopaminergic, systems. on a Symposium on Thirst we have not However, we were also reminded that called the volume by this title because there are cholinergic drinking systems in thirst as such, a subjective human sensa- the brain, at least of the rat, and that tion, is not in fact discussed in these pages. vasopressin increases the sensitivity of The main section headings in the list of drinking systems in the brain of the dog. contents give an idea of the topics dealt An 'apres Cannon' role for oropharyn- with and it is evident from these that a geal factors in the control of water intake is large number of contributions deal with becoming firmly established. There is a the possible role of the renin-angiotensin need to take water by mouth. The self-in- system in the control of water intake.
One travenous injection experiments described difficulty until now in accepting the sugges- here make this very clear.
Contents
Section 1. Introduction.- Thirst and Sodium Appetite in the Regulation of the Body Fluids.- Section 2. Oropharyngeal and Gastric Influences in Drinking.- Lingual Stimulation and Water Intake.- Systemic Versus Oral and Gastrointestinal Metering of Fluid Intake.- Reduction of Saline Intake in Adrenalectomized Rats during Chronic Intragastric Infusions of Saline.- Section 3. Vasopressin and Drinking.- Mechanisms of Hypovolaemic Thirst and Interactions between Hypovolaemia, Hyperosmolality and the Antidiuretic System.- A Radioimmunoassay for Plasma Antidiuretic Hormone and Its Application in a Case of Hypopituitarism Associated with a Loss of Thirst.- Studies on Drinking-Feeding Interactions in Rats with Hereditary Hypothalamic Diabetes Insipidus.- Section 4. Comparative Aspects of the Regulation of Water Intake.- Cellular Dehydration as a Stimulus to Drinking in the Common Iguana, Iguana Iguana.- Section 5. Catecholaminergic Mechanisms and Peripheral Aspects of the Renin-Angiotensin System in Drinking.- Brain Catecholamines and Thirst.- Noradrenergic and Dopaminergic Influences on Thirst.- The Effects of Angiotensin II, Renin and Isoprenaline on Drinking in the Dog.- The Elevation of Endogenous Angiotensin and Thirst in the Dog.- Evidence against the Postulated Role of the Renin-Angiotensin System in Putative Renin-Dependent Drinking Responses.- Relationships between Increase in Plasma Renin Activity and Drinking Following Different Types of Dipsogenic Stimuli.- Drinking Induced by Direct or Indirect Stimulation of Beta-Receptors: Evidence for Involvement of the Renin-Angiotensin System.- Section 6. Central Mechanisms in ReninAngiotensin-Induced Drinking.- Renin, Angiotensin and Drinking.- The Mechanism of Thirst-Induction by Intrahypothalamic Renin.- Angiotensin as Dipsogen.- The Role of the Cerebral Ventricular System in Angiotensin-Induced Thirst.- Subfornical Organ Involvement in Angiotensin-Induced Drinking.- Evidence that the Lateral Hypothalamus and Midbrain Participate in the Drinking Response Elicited by Intracranial Angiotensin.- Angiotensin-Induced Drinking in the Cat.- Section 7. Salt Appetite.- Central Mediation of Water and Sodium Intake: A Dual Role for Angiotensin?.- Conditioned and Pseudoconditioned Thirst and Sodium Appetite.- Thirst and Salt Appetite in Experimental Renal Hypertension of Rats.- Section 8. Other Aspects of Thirst.- Classical Conditioning of Consumatory Behaviour.- The Chemical and Behavioural Specificity of Cholinergic Stimulation of the Tractus Diagonalis.- Increased Drinking in Rats After Isoniazid Withdrawal.- Section 9. Conclusions.- Summary and Comment.- Outlook.- Author Index.
