Full Description
"The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins."
Contents
ADAR Proteins: Structure and Catalytic Activity.- ADAR Proteins: Double-stranded RNA and Z-DNA Binding Domains.- Editing of Neurotransmitter Receptor and Ion Channel RNAs in the Nervous System.- Modulation of Micro RNA Expression and Function by ADARs.- Nuclear Editing of mRNA 3'-Untranslated Regions.- Control of ADAR1 Editing of Hepatitis Delta Virus RNAs.- Bioinformatic Approaches for Identification of A-to-I Editing Sites.- ADARs, Viruses and Innate Immunity.- Role of ADARs in Mouse Development.- Regulation and Functions of ADAR in Drosophila.- Subject index
