Description
(Text)
Hearing Impairment is among the most common neurosensory deficit in humans. World wide more than 250 million people suffer from hearing impairment. This high ratio offer more attention to this problem of Human race. With the emergence of Genomics, our understanding towards the hereditary hearing loss has become more extensive. Role of different genes, their molecular organization, function and mutations, giving an insight of disease development. the study of hearing impairment provide a unique opportunity to deal with two objects simultaneously;1) underlying the pathogenic process in each form of deafness and 2) identification of causative genes and cellular mechanism of hearing. Deafness has many Genetic and Environmental causes. Genetic Hearing Impairment can be classified as Syndromic (30%)and Non-Syndromic (70%)genetic defect.More than 50 nuclear genes have been identified associated with Non-Syndromic Hearing impairment. This high degree of genetic heterogeneity reflects thegreat diversity of specialized proteins that are required to make sense of Sound
