Signal Transduction by Integrins (Molecular Biology Intelligence Unit)

Defilippi, P./ Gismondi, a./ Santoni, A.

Springer-Verlag Berlin and Heidelberg GmbH & Co. K（1997/10発売）

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製本 Hardcover:ハードカバー版／ページ数 200 p.
言語 ENG
商品コード 9783540633617
DDC分類 571.64

Full Description

Examining the mechanisms of intracellular signalling by integrins, this work provides an organic view of these mechanisms through discussion of current literature. Topics covered include the structure and function of integrins, regulation of gene expression by integrins, and action of protein tyrosine kinases pathways.

Integrin structure and function; activation of protein tyrosine kinases pathway; activation of the ras-MAPkinases pathway; phospholipases and the phosphoinositol pathway; regulation of Ca++ transients, Na+/H+ antiporter and electric signals; integrins and the RHO family GTPases pathway; regulation of gene expression by integrins; integrin-dependent regulation of cell growth and apoptosis; cross talk between integrins and membrane receptor in cell growth, immune response inflammation and blood clotting.