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Full Description
This book constitutes the first comprehensive discussion and collection of facts and functions of unconventional secretory pathways, some of which are of importance in human disease and pathology. The function of ABC transporters in these processes is also discussed. This comparison of common aspects and similarities in all living cells - from bacteria to man - is an excellent reference book with "textbook" character.
Contents
1. Protein Secretion in Gram-Negative Bacteria.- 2. Unusual Protein Secretion and Translocation Pathways in Yeast: Implication of ABC Transporters.- 3. Secretion of Mammalian Proteins That Lack a Signal Sequence.- 4. The Transporters Associated with Antigen Processing (TAP).- 5. Mammalian ABC Transporters and Leaderless Secretion: Facts and Speculations.- 6. Secretory Lysosomes and the Production of Exosomes.



