Full Description
Interaction of antigen antibody complexes with cells via specific immunoglobulin Fc receptors (FcR) triggers major immunological reactions, such as efficient uptake of antigen, phagocytosis of microorganisms, cytotoxicity towards tumour- or virus-infected cells, and mast cell derangulation and inflammation. This book reviews the FcR for the different immunoglobulin isotypes, focusing on the structural bases of their biological functions.
