Full Description
Dedicated to Professor Albert Herz, an investigator in opioid research, this book provides information on the biology of exogenous and endogenous opioids. Contributions discuss recent advances and provide systematic, up-to-date reviews of the physiology and pharmacology of opioids, as well as on the cellular and molecular mechanisms underlying opioid actions. In recognition of the diverse methodologies now available to researchers, each chapter details the approaches used to address a specific issue and provides an indepth analysis of the data obtained by these various experimental approaches. The clinical relevance of recent findings, as well as future directions, in opioid research are also discussed. This volume aims to be a sourcebook for researchers, clinicians, and students interested in opioids and peptidergic systems. This research monograph on neuroscience, biochemistry, pharmacology is intended for researchers, advanced students, clinicians.
Contents
General aspects; opioid receptor biochemistry and signal transduction; CNS opioidergic systems; distribution and modulation; functional aspects; opioid tolerance and dependence.
