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Contents: Part 1: Current Drugs.- Inflammatory Mechanisms.- ß-Adrenoceptor Agonists. Anticholinergic Bronchodilators... Part 2: Future Drugs.- New Bronchodilator Drugs.- Selective Phosphodiesterase Inhibitors in the Treatment of Respiratory Disease.- Cytokine Modulators...
The aim of the book is to provide an in-depth review of our current understanding of the pathogenesis of both asthma and COPD. This volume also discusses the promising new options for pharmacological intervention of these diseases. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this important area of lung biology.
1. Current Drugs.- ?-Adrenoceptor Agonists.- Anticholinergic Bronchodilators.- Theophylline in the Treatment of Respiratory Disease.- Corticosteroids.- Mediator Antagonists and Anti-Allergic Drugs.- 2. Future Drugs.- New Bronchodilator Drugs.- Selective Phosphodiesterase Inhibitors in the Treatment of Respiratory Disease.- Cytokine Modulators.- Inhibitors of Leucocyte-Endothelial Adhesion as Potential Treatments for Respiratory Disease.- New Antiallergic Drugs.- Pharmacogenetics, Pharmacogenomics and Gene Therapy.- Evaluation of New Drugs for Asthma and COPD: Endpoints, Biomarkers and Clinical Trial Designs.- Novel Anti-inflammatory Therapies.