This richly-illustrated atlas-like book provides a foundation for the biological and molecular understanding of how the mammary gland develops and how breast cancer originates. The main goal is to comprehensively review in ten chapters fundamental knowledge in breast cancer. New paradigms are described in which induction of differentiation in the mammary gland can promote prevention and cure of breast cancer. The text is extremely helpful both for clinicians treating patients and researchers looking for new avenues of development.
Epidemiology of breast cancer.- The breast as a developing organ.- Endocrine control of the breast.- The role of estrogens in breast cancer.- Pathogenesis of breast cancer.- Prognostic and predictive factors in breast cancer.- The impact of the human genomic project on breast cancer.- The role of experimental models of breast cancer.- Preventive strategies in breast cancer.- New paradigms in the prevention of breast cancer.- Biological laws that determine the susceptibility and refractoriness of the breast to cancer.