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Full Description
A systematic catalog of over 120 electrochemical reactions for organic synthesis
Electrosynthesis has experienced a significant revival as a viable route toward green and sustainable organic synthesis. Electrochemical Strategies in Organic Synthesis, written by Goutam Brahmachari, a prolific author and distinguished professor of organic chemistry, systematically catalogs more than 120 electrochemical reactions for forming carbon-carbon and carbon-heteroatom bonds, resulting in a broad spectrum of biorelevant organic compounds.
Each chapter addresses a specific reaction type, presenting the general reaction scheme, detailed reaction conditions, representative compound examples with chemical structures, mechanism, and critical discussion. Coverage spans C-C, C-N, C-O, C-F, C-S, C-Se, and C-P bond formations leading to functionalized aliphatic, aromatic, alicyclic compounds, and heterocycles.
The book also contains:
Detailed mechanistic discussions and reaction condition parameters for each electrochemical protocol to support laboratory implementation
Critical evaluation of each method's merits, demerits, and sustainability aspects compared with conventional synthetic approaches
Coverage of C-H functionalization and cross-coupling strategies applied to medicinally relevant heterocyclic scaffold construction
References and representative chemical structures throughout, enabling rapid identification of applicable reactions for target compounds
Designed for organic chemists, process chemists, and medicinal chemists working in both academia and industry, this reference provides the systematic organization and practical detail needed to identify, evaluate, and implement electrochemical methods for efficient and sustainable bond-forming reactions.
Contents
About the Author xxiii
Foreword xxvii
Preface xxix
1 Electrochemical Strategies in Organic Synthesis: An Introduction 1
1.1 Introduction 1
1.2 Electrochemistry-Driven Organic Synthesis-A Step Forward 2
1.3 Overview of the Book 3
1.4 How to Read 3
1.5 Concluding Remarks 4
2 Electrochemistry-Driven Synthesis of Functionalized Heterocyclic Compounds 9
2.1 Introduction 9
2.2 Electrochemistry-Driven Synthesis of Functionalized Heterocyclic Compounds 10
2.3 Concluding Remarks 118
3 Electrochemistry-Driven Synthesis of Functionalized Aliphatic and Aromatic Compounds 163
3.1 Introduction 163
3.2 Electrochemistry-Driven Synthesis of Functionalized Aliphatic and Aromatic Compounds 163
3.3 Concluding Remarks 207
4 Electrochemistry-Driven Synthesis of Functionalized Organofluorine Compounds 225
4.1 Introduction 225
4.2 Electrochemistry-Driven Synthesis of Functionalized Organofluorine Compounds 227
4.3 Concluding Remarks 245
5 Electrochemistry-Driven Synthesis of Functionalized Organophosphorus Compounds 255
5.1 Introduction 255
5.2 Electrochemistry-Driven Synthesis of Functionalized Organophosphorus Compounds 255
5.3 Concluding Remarks 280
6 Electrochemistry-Driven Synthesis of Functionalized Organochalcogenated Compounds 289
6.1 Introduction 289
6.2 Electrochemistry-Driven Synthesis of Functionalized Organochalcogenated Compounds 289
6.3 Concluding Remarks 398
References 398
Index 437
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