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Full Description
Intended as an introduction for scientists and professionals working in drug discovery and deveopment, the first part of the book reviews recent therapy developments in diabetes and obesity treatment.
The second part survey important drug classes, including both peptide drugs and small molecule drugs such as GLP-1 receptor agonists, GIP antagonists and poly-agonists. The last part of the book is devoted to selected case studies which provide insights into the discovery of recently approved drugs.
Contents
GENERAL ASPECTS
Diabetes therapies overview
Obesity therapies overview
DRUG CLASSES
GIP agonists/antagonists: Biological aspects
Trends within the field of insulin
GLP1 receptor agonists; small molecules, peptides
NPY receptors as targets for diabetes and obesity
Amylin and PrrP
Poly-agonists for the treatment of diabetes and obesity
Emerging targets: FGF21, MC4, leptin, ghrelin, leap2
Oral antidiabetics beyond GLP1R agonists
CASE STUDIES
Tirzepatide
Dasiglucagon
Teplizumab



