Full Description
The book series Nanomaterials for the Life Sciences, provides an in-depth overview of all nanomaterial types and their uses in the life sciences. Each volume is dedicated to a specific material class and covers fundamentals, synthesis and characterization strategies, structure-property relationships and biomedical applications. The series brings nanomaterials to the Life Scientists and life science to the Materials Scientists so that synergies are seen and developed to the fullest. Written by international experts of various facets of this exciting field of research, the series is aimed at scientists of the following disciplines: biology, chemistry, materials science, physics, bioengineering, and medicine, together with cell biology, biomedical engineering, pharmaceutical chemistry, and toxicology, both in academia and fundamental research as well as in pharmaceutical companies. VOLUME 9 - Carbon Nanomaterials This volume describes Carbon Nanomaterials, from syntheses to characterization, as well as their application to the Life Sciences, Carbon Nanomaterials can be used in a variety of fields, from tissue engineering to cancer treatment.
Contents
Preface PART I: Overview of Synthesis, Characterization, and Applications in Biomedicine CARBON NANOMATERIALS: SYNTHETIC APPROACHES Introduction General Concepts on the Synthesis of Carbon (Nano-)Materials Synthesis from Solid Precursors Catalytic Chemical Vapor Deposition Purification Techniques Importance of Defects and Curvature for Further Functionalization Functionalization: Creating Anchoring Points for Bioactive Molecules Conclusion and Outlook NANOCARBONS: CHARACTERIZATION TOOLS Introduction Diffraction Techniques Imaging Spectroscopy Summary SYNTHESIS, CHARACTERIZATION, AND BIOMEDICAL APPLICATIONS OF GRAPHENE Introduction Synthesis of Graphene Characterization of Graphene Biomedical Applications of Graphene Conclusions CAR$BON NANOHORNS AND THEIR BIOMEDICAL APPLICATIONS Introduction Structure and Properties Functionalization Biomedical Applications Conclusions BIO-INSPIRED MAGNETIC CARBON MATERIALS Introduction Allotropic Forms of Carbon Magnetism in Diamond Magnetism in Graphite Magnetism in Carbon Nanotubes/Fullerenes Magnetism in Graphene Conclusion MULTI-WALLED CARBON NANOTUBES FOR DRUG DELIVERY Introduction Gene Therapy Antibacterial Therapy Wound Healing Chemotherapy Summary and Future Perspectives CARBON NANOTUBE-BASED THREE-DIMENSIONAL MATRICES FOR TISSUE ENGINEERING Introduction Carbon Nanotubes Carbon Nanotubes for Matrix Enhancement Cellular Responses to CNT-Based Matrices CNT Engineering into Three-Dimensional Matrices Summary ELECTROCHEMICAL BIOSENSORS BASED ON CARBON NANOTUBES Introduction CNT Properties Electrochemical Biosensing CNT-Based Electrode Fabrication Applications Conclusions SINGLE-WALLED CARBON NANOTUBE BIOSENSORS Introduction The Sensing Mechanism of Nanotube Biosensors The Immobilization of Biomolecules on SWNTs Various Receptors for Nanotube Biosensors The Application of Nanotube Biosensors to Pathogen Detection The Future of Nanotube Biosensors ENVIRONMENTAL IMPACT OF FULLERENES Introduction Methods Used to Prepare Fullerene Suspensions Toxicological Data Relating to Fullerene Possible Emission Sources of C60 The Environmental Fate of C60 Fullerenes in the Environment Conclusion COMPUTATIONAL TOOLS FOR THE BIOMEDICAL APPLICATION OF CARBON NANOMATERIALS Introduction Simulation Methods Results and Discussion Future Perspectives Executive Summary PART II: Overview of Applications in Cancer CARBON NANOTUBES FOR CANCER THERAPY Introduction Hyperthermia for Cancer Treatment CNTs for Drug Delivery Imaging Using CNTs CNT-Related Toxicity Summary and Future Perspective CANCER TREATMENT WITH CARBON NANOTUBES, USING THERMAL ABLATION OR ASSOCIATION WITH ANTICANCER AGENTS Introduction Use of Nanotubes as Heated Particles Use of Anticancer Agents Associated with Nanotubes Summary Future Perspective CARBON NANOTUBES FOR TARGETED CANCER THERAPY Introduction Cancer Conventional Cancer Chemotherapy versus Nanocarrier-Mediated Drug Delivery Carbon Nanotubes as Drug-Delivery Vehicles Cellular Uptake of CNTs Functionalization of CNTs with Polyethylene Glycol Targeting of Cancers Targeted Cancer Therapy Employing CNTs and a Critique of Current Studies Summary and Future Perspective APPLICATION OF CARBON NANOTUBES TO BRAIN TUMOR THERAPY Introduction The Current Challenge of Brain Tumor Therapy The Characteristics of CNTs for Biological Applications Strategies of Application of CNTs to Brain Tumor Therapy Toxicity Issues of CNTs in Brain Tumor Therapy Conclusions and Future Directions CARBON NANOTUBES IN CANCER THERAPY, INCLUDING BORON NEUTRON CAPTURE THERAPY (BNCT) Introduction Carbon Nanotubes in the Treatment of Cancer BNCT and Its Development through Nanotechnology The Role of Carbon Nanotubes in BNCT Summary and Future Outlook FULLERENES IN PHOTODYNAMIC THERAPY Introduction Photodynamic Therapy Fullerenes as Photosensitizers Anticancer Effects of Fullerenes Fullerenes for Antimicrobial Photoinactivation Summary and Future Perspectives
