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基本説明
A must-have for everyone working with Aspirin.
Full Description
Written by a leading expert on Aspirin-related research, this is the first comprehensive treaty of the history, pharmacological effects and clinical applications of one of the most successful drugs ever. The text is written with a wide audience in mind and to be readily understandable for clinicians as well as biomedical researchers and pharmacologists alike. The content is up to date and includes the latest results of clinical and academic research, with a balanced view on the disputed properties of this famous drug.
Contents
TABLE OF CONTENTS 1. GENERAL ASPECTS 1.1 HISTORY 1.1.1 WILLOW BARK ABSORPTION AND DISTRIBUTION 2.1.2 BIOTRANSFORMATION AND EXCRETION 2.2 INFLAMMATION, PAIN AND FEVER 2.3.3 ASPIRIN AND MALIGNANCIES 3. TOXICITY AND DRUG SAFETY 3.1 SYSTEMIC SIDE-EFFECTS 3.1.1 ACUTE AND CHRONIC TOXICITY 3.1.2 BLEEDING DISORDERS 3.1.3 SAFETY PHARMACOLOGY IN PARTICULAR LIFE SITUATIONS 3.2 ORGAN TOXICITY 3.2.1 GASTROINTESTINAL (GI) TRACT 3.2.2 KIDNEY 3.2.3 LIVER 3.2.4 AUDIOVESTIBULAR SYSTEM ASPIRIN HYPERSENSITIVITY (WIDAL'S SYNDROME) 3.3.2 URTICARIA/ANGIOEDEMA, STEVENS-JOHNSON- AND LYELL-SYNDROME 3.3.3 REYE SYNDROME 4. CLINICAL VASCULAR DISEASE 4.1.2 CEREBROVASCULAR DISEASES 4.1.3 PERIPHERAL ARTERIAL DISEASE (PAD) 4.1.4 VENOUS THROMBOSIS 4.1.5 PREECLAMPSIA 4.1.6 ASPIRIN "RESISTANCE" 4.2 PAIN, FEVER AND INFLAMMATORY DISEASES 4.2.1 KAWASAKI DISEASE 4.3 FURTHER CLINICAL INDICATIONS 4.3.1 COLORECTAL CANCER 4.3.2 ALZHEIMER DISEASE ABBREVIATIONS (NO ACRONYMS FOR CLINICAL STUDIES) ACRONYMS FOR CLINICAL STUDIES INDEX TERMS (PRELIMINARY)



