基本説明
分子・細胞生物学、分子医学の総合レファレンス“Encyclopedis of Molecular Cell Biology and Molecular Medicine”１６vols.からタンパク質研究に関わる記事をまとめた貴重な資料。３人のノーベル賞受賞者を含む寄稿で、タンパク質構造、モデリング、発現、分析など幅広いトピックを収録。
Volume 1: I STRUCTURE AND FUNCTION- Macromolecules, X-Ray Diffraction of Biological; Protein NMR Spectroscopy; Electron Microscopy of Biomolecules; Prions; Alzheimer's Disease.. II MODELLING AND DESIGN- Protein Modeling; Synthesis of Peptide Mimetics and their Building Blocks; Design and Application of Synthetic Peptides.. III EXPRESSION, SYNTHESIS AND DEGRADATION- Ribosome, High Resolution Structure and Function; Ubiquitin-Proteasome System for Controlling Cellular Protein Levels...
Description
(Text)
With three Nobel Laureates contributing to this invaluable collection of high-quality articles, carefully selected from the highly praised R.A. Meyer's Encyclopedia, these two volumes cover a wide range of topics in protein research. Clearly divided into sections on structure, modeling, expression, analysis and others, the chapters are designed to aid readers of all levels of expertise: Each chapter includes a glossary of the most important keywords, a concise summary of the article concerned and comprehensive references for further reading. Similarly, the uniform structure of the articles makes them very easy to use, resulting in a ready reference for molecular and cell biologists, biochemists, biophysicists, and biotechnologists, as well as those working in the pharmaceutical and biotechnological industries.
(Table of content)
VOLUME 1
I STRUCTURE AND FUNCTION
Macromolecules, X-Ray Diffraction of Biological
Protein NMR Spectroscopy
Electron Microscopy of Biomolecules
Circular Dichroism in Protein Analysis
Protein Structure Analysis: High-throughput Approaches
Aggregation, Protein
Prions
Alzheimer's Disease
Chaperones, Molecular
Motor Proteins
DNA-Protein Interactions
II MODELLING AND DESIGN
Protein Modeling
Synthesis of Peptide Mimetics and their Building Blocks
Design and Application of Synthetic Peptides
Synthetic Peptides: Chemistry, Biology, and Drug Design
III EXPRESSION, SYNTHESIS AND DEGRADATION
Ribosome, High Resolution Structure and Function
Ubiquitin-Proteasome System for Controlling Cellular Protein Levels
Plant-based Expression of Biopharmaceuticals
Cell-free Translation Systems
VOLUME 2
I ANALYTICAL TECHNIQUES
HPLC of Peptides and Proteins
Protein Purification
Gel Electrophoresis, 2D-Difference
Proteomics
Mass Spectrometry-based Methods of Proteome Analysis
Protein Microarrays
Informatics(Computational Biology)
Nucleic Acid and Protein Single Molecule Detection and Characterization
Footprinting Methods to Examine the Structure and Dynamics of Proteins
II SIGNALLING AND REGULATION
Biological Regulation by Protein Phosphorylation
Intracellular Signaling in Cancer
Receptor Biochemistry
Signal Transduction Mediated by Heptahelical Receptors and Heterotrimeric G Proteins
Growth Factors
Cytokines: Interleukins
Viral Inhibitors and Immune Response Mediators: The Interferons
Molecular Mediators: Cytokines
(Author portrait)
Robert A. Meyers obtained his Ph.D. in Chemistry at the University of California at Los Angeles. He was a post-doctoral fellow at the California Institute of Technology and has more than 17 patents, 50 technical papers and 12 books to his name. As Editor-in-Chief he conceived and edited several ambitious multivolume reference works.
