The Way of Synthesis : Evolution of Design and Methods for Natural Products （2008. 550 p. 24 cm）

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The Way of Synthesis : Evolution of Design and Methods for Natural Products （2008. 550 p. 24 cm）

Hudlicky, Tomas/ Reed, Josephine W.

ウェブストア価格 ¥24,713（本体¥22,467）
Wiley-VCH（2008発売）
外貨定価 EUR 99.90
ポイント 224pt

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製本 Paperback:紙装版/ペーパーバック版／ページ数 600 p.
商品コード 9783527314447

Full Description

This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds. With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry.

"I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication." (Victor Snieckus)

INTRODUCTION The History of Synthesis

Milestones in Organic Sythesis

STRATEGY AND TACTICS

Principles and Issues Impacting Synthesis (Strategy)

Principles and Issues Impacting Design (Strategy)

Principles and Issues of Methods (Tactics)

COMPARATIVE DESIGN: CLASSICS IN TERPENE SYNTHESIS

Juvenile Hormones

Cedrenes

Zizaanes

Hydroazulenes

Vernolepin

Triquinanes

Compactin

Aphidicolin

Miscellaneous Diterpenes

Taxol

COMPARATIVE DESIGN: CLASSICS IN ALKALOID SYNTHESIS

Lycopodium Alkaloids

Daphniphyllum Alkaloids, Daphnilactone A

Pyrrolizidine Alkaloids

Amaryllidaceae Alkaloids

Morphine

Indole Alkaloids

MISCELLANEOUS SYNTHESES

Maytansine

Palytoxin

Brevetoxin B

Indinavir

OUTLOOK