基本説明
An introduction.
Full Description
This is a fascinating introduction to the topic. Spanning the spectrum of nucleic acid chemistry, carbohydrates, peptides, molecular recognition, biosynthesis and natural biosynthesis, right up to medical and biophysical chemistry, the book provides advanced students and those already working in the field with a balanced overview.
In more than 30 contributions, a new generation of recognized scientists gives an account of the latest research in such areas as
* Artificial receptors for the stabilization of ?-sheet structures
* Carbohydrate recognition by artificial receptors
* Combinatorial chemistry as a tool for the discovery of catalysts
* The interaction of NO and peroxynitrite with hemoglobin and myoglobin
* Inhibitors against human mast-cell-tryptase as a potential approach to conquering asthma
* The selectivity of DNA replication.
A readily accessible survey for everyone wishing to stay abreast of developments.
With a Foreword by Ronald Breslow.
Contents
STRUCTURE OF BIOMOLECULES
b-amino acids in Nature: Biosynthesis and Biology
Artificial receptors for the stabilization of b-sheet structures
Conformational equilibria of RNA
Conformational restriction of sphingolipids
Stabilization of peptide-microstructures by coordniation of metal ions
Synthesis and application of proline and piccolic acid derivatives: tools for stabilization of peptide secondary structures.
INTERMOLECULAR INTERACTIONS (BINDING)
Artificial rotary motors at the molecular level
Carbohydrate recognition by artificial receptors
Synthetic approaches to study carbohydrate-lectin interactions
Cyclopeptides as macrocyclic host molecules for charged guests
Combinatorial chemistry as a tool for the development of molecular receptors for small peptides
The design of new binding motifs for c-terminal peptides
INTERACTION OF SMALL MOLECULES WITH BIOLOGICAL SYSTEMS (FUNCTION)
Modulation of biochemical processes by synthetic hosts for substrates
Interaction of NO and peroxynitrite with hemoglobin and myoglobin
Oxidative splitting of pyrimidine cyclobutane dimers
Inhibitors against human mast-cell-tryptase: a potential approach to attack asthma?
Selectivity of DNA replication
Acridizinium salts and their photophysical interaction with DNA
DNA-detection in homogeneous solution
