Full Description
This book, in Q&A format, addresses a wide range of clinically relevant
topics and issues in Nonmalignant Hematology, or "Benign Hematology," with a
view to offering a robust, engaging tool that will assist every hematologist and
oncologist (pediatric and adult equally) in making decisions during day-to-day
practice. The entire spectrum of the specialty is covered in more than 60
exceptional chapters written by acknowledged authorities in the field. The
content is organized into well-designed broad sections on red cell disorders,
platelet and coagulation disorders, coagulopathy in systemic diseases,
thromboembolic disease and its management (including surgical), immune system
and related disorders, hemostasis and thrombosis during pregnancy and in the
newborn and elderly, and Transfusion Medicine. A key aspect of the book is the
opportunity it affords expert physicians to express well-reasoned opinions
regarding complex issues in Nonmalignant Hematology. Readers willfind that it
provides a practical and immediately applicable compendium of answers to often
complex and vexing questions. It will appeal to residents, fellows, house
officers and more experienced practitioners around the globe.
Contents
Part
1. Red Blood Cells.- Evaluation of
anemia in children and adults.- Iron cycle and pathophysiology of iron homeostasis.- Porphyrias: Diagnosis and
management.- Disorders of hemoglobin synthesis: Pathophysiology and diagnostic
evaluation.- Management of thalassemias.- Allogeneic hematopoietic cell
transplant in ß-thalassemia major.- Sickle cell disease: Prevention of
complications.- Sickle cell disease: Management of complications.- Allogeneic
hematopoietic cell transplant in sickle cell disease.- Anemia of inflammation.-
Iron overload: Diagnosis, complications and management.- Megaloblastic and
nutritional anemias.- Sideroblastic anemias: Diagnosis and management.- Primary
autoimmune warm antibody hemolytic anemias.- Intrinsic hemolytic anemias: Pathophysiology,
diagnosis and management.- Part 2. Platelets and Coagulation System.- Platelet
disorders: Diagnostic tests and their interpretations.- Inherited platelet
disorders: Diagnosis and management.- Acquired platelet disorders: Diagnosis
and management.- Immune mediated thrombocytopenia.- Coagulation cascade and
fibrinolysis pathway: Assessment in the laboratory.- Abnormalities in
fibrinolysis pathway and clinical implications.- Congenital disorders of
fibrinogen: Clinical presentations, diagnosis and management.- Hemophilias A
and B: Diagnosis and management.- Coagulation factor inhibitors: Diagnosis and
management.- Rare coagulation factor
deficiencies: Diagnosis and management.- von Willebrand disease: Differential
diagnosis and diagnostic approach to specific subtypes.- von Willebrand
disease: Prevention of complications and management of the disease.- Antifibrolytics:
Indications and precautions.- Gene therapy for bleeding disorders.- Part 3. Coagulopathy
in Systemic Diseases.- Disseminated intravascular coagulopathy.- Coagulopathy
in critically ill subjects.- Trauma-associated coagulopathy.- Coagulation
related issues in malignant hematology: Diagnosis and management.- Unmet clinicalneeds of antithrombotic treatment in
BCR/ABL negative myeloproliferative neoplasms.- Bleeding and
thrombosis in a cancer patient.- Management of surgical patient with thrombotic
and bleeding diathesis.- Part 3. Thrombosis and Therapeutics.- Prevention and
treatment of arterial thromboembolism.- mes New Roman","serif"">Prevention of venous thromboembolism.- Diagnostic,
prognostic and therapeutic challenges in venous thromboembolisim.- Complications
of venous thromboembolic disease.- Hereditary
thrombophilias: Pathophysiology, timing of testing and familiar testing.- Anti-phospholipid
antibodies and syndrome: Complexities in diagnosis and management.- Unidentifiable
thrombophilias.- Anticoagulation drugs: Indications, therapeutic monitoring and
antidotes.- Heparin induced thrombocytopenia: Diagnosis and management.- Thrombotic
thrombocytopenic purpura and hemolytic uremic syndrome.- Surgical treatment of
thromboembolic disease.- Part 4. Immune System and Related Disorders.- Nonmalignant
leukocyte disorders.- Primary immunodeficiency disorders: Diagnosis and
management.- Disorders of phagocytic function:
Diagnosis and treatment.- Inherited bone marrow failure syndromes.- Hemophagocytic lymphohistiocytosis: Diagnosis
and management challenges.- Lysosomal storage disorders: Hematology
perspective.- Cryoglobulins and
cryoglobulinemia.- Part 5. Hemostasis and Thrombosis in Pregnancy, Newborn
and Elderly.- Reproductive issues in women with bleeding and thrombotic
disorders.- Pregnancy in subjects with
hemoglobinopathies: Precautions and management.- Neonatal thrombosis and coagulopathies.-
Bleeding and thrombosis in elderly.- Part 6. Transfusion Medicine.- Transfusion
support: Indications, efficacy and complications.- Human blood antigens and
antibodies: Diagnostic and therapeutic implications.- Therapeutic apheresis in
hematologic disorders: When and Why?
