Peptides and Peptide-based Biomaterials and their Biomedical Applications (Advances in Experimental Medicine and Biology)

Sunna, Anwar (EDT)/ Care, Andrew (EDT)/ Bergquist, Peter L. (EDT)

Springer International Publishing AG（2017/11発売）

• 製本 Hardcover:ハードカバー版／ページ数 300 p.
• 商品コード 9783319660943

Full Description

Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as β-sheet fibril-forming peptides and α-helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.

Contents

Programmable Bio-Surfaces for Biomedical Applications.- Solid-binding Peptides in Biomedicine.- Molecular Modelling of Peptide-based Materials for Biomedical Applications.- Design principles of peptide based self-assembled nanomaterials.- Bioprinting and Biofabrication with Peptide and Protein Biomaterials.- Peptides as Bio-Inspired Molecular Electronic Materials.- Peptide-Based Materials for Cartilage Tissue Regeneration.- Peptides and Drug Delivery.- Peptide Lipidation - A Synthetic Strategy to Afford Peptide Based Therapeutics.- Molecular Engineering of Conus Peptides as Therapeutic Leads.- Uptake Mechanism of Cell-Penetrating Peptides.- Empowering the Potential of Cell-Penetrating Peptides for Targeted Intracellular Delivery via Molecular Self-Assembly.- The Current Role of Cell-Penetrating Peptides in Cancer Therapy.