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Full Description
This book addresses the need for a unified framework describing how soft computing and machine learning techniques can be judiciously formulated and used in building efficient pattern recognition models. The text reviews both established and cutting-edge research, providing a careful balance of theory, algorithms, and applications, with a particular emphasis given to applications in computational biology and bioinformatics. Features: integrates different soft computing and machine learning methodologies with pattern recognition tasks; discusses in detail the integration of different techniques for handling uncertainties in decision-making and efficiently mining large biological datasets; presents a particular emphasis on real-life applications, such as microarray expression datasets and magnetic resonance images; includes numerous examples and experimental results to support the theoretical concepts described; concludes each chapter with directions for future research and a comprehensive bibliography.
Contents
Introduction to Pattern Recognition and Bioinformatics.- Part I Classification.- Neural Network Tree for Identification of Splice Junction and Protein Coding Region in DNA.- Design of String Kernel to Predict Protein Functional Sites Using Kernel-Based Classifiers.- Part II Feature Selection.- Rough Sets for Selection of Molecular Descriptors to Predict Biological Activity of Molecules.- f -Information Measures for Selection of Discriminative Genes from Microarray Data.- Identification of Disease Genes Using Gene Expression and Protein-Protein Interaction Data.- Rough Sets for Insilico Identification of Differentially Expressed miRNAs.- Part III Clustering.- Grouping Functionally Similar Genes from Microarray Data Using Rough-Fuzzy Clustering.- Mutual Information Based Supervised Attribute Clustering for Microarray Sample Classification.- Possibilistic Biclustering for Discovering Value-Coherent Overlapping d -Biclusters.- Fuzzy Measures and Weighted Co-Occurrence Matrix for Segmentation of Brain MR Images.
